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MAB2075Z Anti-Integrin β6 Antibody, clone R6G9, azide free

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MAB2075Z
100 µg  
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      개요

      주요 사양표

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HFC, IPMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMAB2075Z
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Integrin β6 Antibody, clone R6G9, azide free
      Alternate Names
      • MAB2075
      Product Information
      FormatPurified
      PresentationSterile-filtered liquid at 1 mg/mL in PBS, containing no preservatives.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Integrin β6 Antibody, clone R6G9, azide free is an antibody against Integrin β6 for use in FC & IP.
      Key Applications
      • Flow Cytometry
      • Immunoprecipitation
      Applications Not Recommended
      • Western Blotting
      • Inhibits Activity/Function
      Application NotesFlow cytometry

      Immunoprecipitation: Effective; however because this antibody is an IgG2a, protein G or rabbit anti-mouse IgG is helpful for capture.

      Immunohistochemistry/immunocytochemistry: The antibody recognizes alphaVbeta6 by immunohistochemistry and immunocytochemistry (acetone fix), but nuclear background staining limits usefulness in these techniques.


      Then antibody is not function blocking and not effective for western blot.

      Optimal working dilutions must be determined by end user.
      Biological Information
      ImmunogenMurine NIH 3T3 cells stably transfected with the human (6 subunit
      CloneR6G9
      HostMouse
      SpecificityMonoclonal antibody MAB2075Z, raised by immunizing Balb/c mice with murine NIH 3T3 cells stably transfected with the human beta6 subunit, recognizes the human beta6 subunit by flow cytometry and is an excellent antibody for immunoprecipitation.
      IsotypeIgG2a
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • ITGB6
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P18564 # Integrin alpha-V/beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands.
      SIZE: 788 amino acids; 85936 Da
      SUBUNIT: Heterodimer of an alpha and a beta subunit. Beta-6 associates with alpha-V. Interacts with FLNB.
      SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
      SIMILARITY: SwissProt: P18564 ## Belongs to the integrin beta chain family. & Contains 1 VWFA domain.
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain frozen at -20°C in undiluted aliquots for up to 12 months.
      Packaging Information
      Material Size100 µg
      Global Trade Item Number
      카탈로그 번호 GTIN
      MAB2075Z 04053252579301