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Merck

MABF287

Anti-FPR1, C-Term Dephospho Antibody, clone NFPRb

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제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
NFPRb, monoclonal
Application:
FACS, ICC, IHC, IP, WB
Citations:
-
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conjugate

unconjugated

Quality Segment

antibody form

purified antibody

clone

NFPRb, monoclonal

purified by

using protein G

species reactivity

mouse, human

concentration

(Please refer to lot specific datasheet.)

technique(s)

flow cytometry: suitable, immunocytochemistry: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable

isotype

IgG1κ

UniProt accession no.

target post-translational modification

unmodified

General description

40 kDa calculated
His-tagged recombinant protein corresponding to human FPR1 near the C-terminus.

Application

Epitope: Near C-terminus

Biochem/physiol Actions

Clone NFPRb selectively detects FPR1 with non-phosphorylated C-terminal tail. Diminished immunoreactivity is an indication of enhanced FPR1 C-terminal tail phosphorylation or neutrophils activation. Clone NFPRb is not reactive toward N-formyl peptide receptor 2 (encoded by FPR2/FPRL1 gene) regardless of its phosphorylation state (PMID 16675446, 17675514, 23873933).

Physical form

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Evaluated by Flow Cytometry in human peripheral blood mononuclear.

Flow Cytometry Analysis: 1.5 µg of this antibody detected FPR1 in human peripheral blood mononuclear.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.




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