수량	카탈로그 번호	주문 설명	포장 단위	기재 가격
			96-Well Plate

수량	카탈로그 번호	주문 설명	포장 단위	기재 가격
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

GR13 Sigma-AldrichAnti-EGFR (Ab-3) Mouse mAb (225)

Anti-EGFR (Ab-3), mouse monoclonal, clone 225 recognizes the ~170 kDa epidermal growth factor receptor protein. It is validated for use in immunoprecipitation.

Anti-EGFR (Ab-3) Mouse mAb (225) MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

CoA
References
Data Sheet

Synonyms: Anti- Epidermal Growth Factor Receptor

Recommended Products

개요

Replacement Information

주요 사양표

Species Reactivity	Host	Antibody Type
H	M	Monoclonal Antibody

가격 및 재고여부

카탈로그 번호	재고 정보	패킹	포장 단위	가격(VAT 별도)	수량
GR13-100UGCN	재고 정보 검색... — 현재 재고 없음 예상 출고 가능일 단종품 제한된 수량 가능 재고여부 확인 재고목록을 보려면 로그인하십시오 예상 출고 가능일 현재 재고 없음 예상 출고 가능일 Remaining: will advise Remaining: will advise 추천사항 고객 서비스로 문의 Contact Customer Service 고객 서비스로 문의 고객 서비스로 문의	Plastic ampoule	100 μg	가격 검색... 가격을 검색할 수 없습니다 Minimum Quantity needs to be mulitiple of Maximum Quantity is 가격 문의 추가 정보 ()이 할인됨 — 가격 문의 고객님의 가격을 보려면 로그인하십시오	재고 조회 —	즐겨찾기에 추가 즐겨찾기에 추가 나의 즐겨찾기에 추가

Description
Overview	Recognizes the ~170 kDa epidermal growth factor receptor protein. For neutralization studies Cat. No. GR13L is recommended.
Catalogue Number	GR13
Brand Family	Calbiochem®
Synonyms	Anti- Epidermal Growth Factor Receptor

References
References	Hunter T. 1984. Nature 311, 414. Reynolds, F.H., et. al 1981. Nature 292, 259. Ushiro, H. and Cohen, S. 1980. J. Biol. Chem. 255, 8363.

Product Information
Form	Liquid
Formulation	In 0.05 M sodium phosphate buffer, 0.2% gelatin.
Negative control	HL-60 cells
Positive control	A-431 cells
Preservative	≤0.1% sodium azide
Quality Level	MQ100

Applications
Application References	Original Clone Kawamoto, T., et al. 1983. Proc. Natl. Acad. Sci. USA 80, 1337. Neutralization Studies Gill, G., et al. 1984. J. Biol. Chem. 259, 7755. Kawamoto, T., et al. 1984. J. Biol. Chem. 259, 7761. Masui, H., et al. 1984. Cancer Res. 44, 1002. Kawamoto, T., et al. 1983. Proc. Natl. Acad. Sci. USA 80, 1337. Sato, J.D., et al. 1983. Biol. Med. 1, 511.
Key Applications	Immunoprecipitation
Application Notes	Immunoprecipitation (1-2 µg per sample) Neutralization Studies (2 µg/ml, see application references; use Cat. No. GR13L)
Application Comments	Shown to inhibit human tumor xenographs in nude mice. It inhibits EGF binding to its receptor and is an antagonist of in vivo EGF-stimulated tyrosine kinase activity. It also inhibits A431 tumor formation in nude mice. For neutralization studies GR13L is recommended. Antibody should be titrated for optimal results in individual systems.

Biological Information
Immunogen	partially purified, human EGFR from A431 cells
Immunogen	Human
Clone	225
Host	Mouse
Isotype	IgG₁
Species Reactivity	Human
Antibody Type	Monoclonal Antibody
Concentration Label	Please refer to vial label for lot-specific concentration

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Blue Ice Only
Toxicity	Standard Handling
Storage	+2°C to +8°C
Do not freeze	Yes

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
카탈로그 번호	GTIN
GR13-100UGCN	04055977228243

Documentation

Anti-EGFR (Ab-3) Mouse mAb (225) Certificates of Analysis

Title	Lot Number
GR13	로트(lot) 번호를 입력하십시오.

References

참고문헌 보기
Hunter T. 1984. Nature 311, 414. Reynolds, F.H., et. al 1981. Nature 292, 259. Ushiro, H. and Cohen, S. 1980. J. Biol. Chem. 255, 8363.

Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	25-October-2007 JSW
Synonyms	Anti- Epidermal Growth Factor Receptor
Application	Immunoprecipitation (1-2 µg per sample) Neutralization Studies (2 µg/ml, see application references; use Cat. No. GR13L)
Description	Purified mouse monoclonal antibody generated by immunizing BALB/c mice with the specified immunogen and fusing splenocytes with NS-1 mouse myeloma cells (see application references). Recognizes the ~170 kDa epidermal growth factor receptor protein.
Background	Epidermal growth factor (EGF) initiates its effects on cell growth through interaction with a 170,000 dalton cell surface glycoprotein receptor. Binding of EGF or transforming growth factor a to the receptor activates a tyrosine-specific protein kinase intrinsic to the EGF receptor protein. The phosphotyrosine content of target cells increases rapidly and the EGF receptor is phosphorylated on tyrosine residues. Subsequent to binding, EGF receptor complexes are internalized and cell proliferation takes place with partially-purified EGF receptor from human A431 epidermal carcinoma cells.
Host	Mouse
Immunogen species	Human
Immunogen	partially purified, human EGFR from A431 cells
Clone	225
Isotype	IgG₁
Species	human, not mouse, not rat
Positive control	A-431 cells
Negative control	HL-60 cells
Form	Liquid
Formulation	In 0.05 M sodium phosphate buffer, 0.2% gelatin.
Concentration Label	Please refer to vial label for lot-specific concentration
Preservative	≤0.1% sodium azide
Comments	Shown to inhibit human tumor xenographs in nude mice. It inhibits EGF binding to its receptor and is an antagonist of in vivo EGF-stimulated tyrosine kinase activity. It also inhibits A431 tumor formation in nude mice. For neutralization studies GR13L is recommended. Antibody should be titrated for optimal results in individual systems.
Storage	+2°C to +8°C
Do Not Freeze	Yes
Toxicity	Standard Handling
References	Hunter T. 1984. Nature 311, 414. Reynolds, F.H., et. al 1981. Nature 292, 259. Ushiro, H. and Cohen, S. 1980. J. Biol. Chem. 255, 8363.
Application references	Original Clone Kawamoto, T., et al. 1983. Proc. Natl. Acad. Sci. USA 80, 1337. Neutralization Studies Gill, G., et al. 1984. J. Biol. Chem. 259, 7755. Kawamoto, T., et al. 1984. J. Biol. Chem. 259, 7761. Masui, H., et al. 1984. Cancer Res. 44, 1002. Kawamoto, T., et al. 1983. Proc. Natl. Acad. Sci. USA 80, 1337. Sato, J.D., et al. 1983. Biol. Med. 1, 511.

Related Products

카탈로그 번호

설명

GR13L

Anti-EGFR (Ab-3) Mouse mAb (225)

가격 및 재고 조회

카테고리

Life Science Research > Antibodies and Assays > Primary Antibodies

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