MABF1497
Anti- CD161 (NK1.1) (mouse), redFluor® 710, clone PK136 Antibody
clone PK136, from mouse, redFluor® 710
동의어(들):
Killer cell lectin-like receptor subfamily B member 1B allele A, CD161 antigen-like family member B, Lymphocyte antigen 55b (Ly-55b), NKR-P1 34, Natural killer cell surface protein NKR-P1B allele SJL/BALB (NKR-P1B), CD161b, CD161 (NK1.1)
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크기 선택
보기 변경
제품정보 (DICE 배송 시 비용 별도)
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
redFluor® 710
Clone:
PK136, monoclonal
Application:
FACS
Citations:
-
biological source
mouse
Quality Segment
conjugate
redFluor® 710
antibody form
purified antibody
antibody product type
primary antibodies
clone
PK136, monoclonal
species reactivity
mouse
technique(s)
flow cytometry: suitable
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
mouse ... Klrb1C(17059)
General description
The PK136 antibody is specific for mouse NK1.1, a type II transmembrane lectin-like receptor and member of the killer cell lectin-like receptor (KLR) family. NK1.1 is prominently expressed on natural killer (NK) cells, and is correlated with NK cytotoxic effects toward virus-infected cells and tumor cells. NK1.1 is expressed on subsets of NKT cells in certain mouse strains (C57BL/6, FVB/N, and NZB), yet absent from others (AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129). Putative subsets of NK cells and their expression of NK1.1 antigen are of continuing interest, including NK1.1+/CD117+ (c-Kit) cells reported to be immunosuppressive for CD8+ T cells in a mechanism involving PD-1 and PD-L1 (Ehlers et al. 2012. Endocrinology. 10: 1247).The PK136 antibody may be used for detection of NK1.1 expression on mouse strains including CE, B6, NZB, C58, Ma/My, ST, SJL, and FVB. The antibody is reported to react with an epitope common to NKR-P1B and NKR-P1C alloantigenic forms of NK1.1 (Carlyle et al. 2006. J. Immunol. 176: 7511-7524).
Anti- CD161 (NK1.1) (mouse), redFluor® 710, clone PK136 Antibody is an antibody against CD161 for use in Flow Cytometry.
Analysis Note
This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.
Flow Cytometry Analysis: 0.125 μg from a representative lot detected CD161 (NK1.1) in one million C57Bl/6 splenocytes.
Flow Cytometry Analysis: 0.125 μg from a representative lot detected CD161 (NK1.1) in one million C57Bl/6 splenocytes.
Other Notes
Concentration: Please refer to lot specific datasheet.
Legal Information
redFluor is a registered trademark of Tonbo Biotechnologies
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저장 등급
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
시험 성적서(COA)
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