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AB15708C3 Anti-Beta III Tubulin, Cy3 Conjugate Antibody

This Anti-Beta III Tubulin, Cy3 Conjugate Antibody is validated for use in ICC for the detection of Beta III Tubulin.

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Research Category: Neuroscience Research Sub-Category: Neuronal & Glial Markers, Neurofilament & Neuron Metabolism Gene Symbol: TUBB3, TUBB4, MC1R, beta-4 UniProt Number: Q13509
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AB15708C3
100 µL  
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      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RICCRbCy3Polyclonal Antibody
      Description
      Catalogue NumberAB15708C3
      DescriptionAnti-Beta III Tubulin, Cy3 Conjugate Antibody
      Background InformationTubulin is one of several members of a small family of globular proteins which polymerize to form cytoskeletal structures called microtubules. The most common members of the tubulin family are α-tubulin and β-tubulin. Tubulin dimers, typically composed of α- and β-tubulin subunits, assemble onto microtubules forming large polymers. β-III tubulin is a unique microtubule subunit that is found expressed almost exclusively in neurons. Due to the unique expression pattern of β-III tubulin it is often utilized as a marker to identify neuronal cells from other brain cells such as glia which do not express it. β-III tubulin also serves as a cytoarchitectural marker since it is primarily found within neurite extensions.
      Product Information
      FormatCy3
      Control
      • Rat E18 cortex cells
      PresentationPurified rabbit polyclonal conjugated to Cy3 in PBS with 0.1% sodium azide and 15 mg/mL BSA.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-Beta III Tubulin, Cy3 Conjugate Antibody is validated for use in ICC for the detection of Beta III Tubulin.
      Key Applications
      • Immunocytochemistry
      Biological Information
      ImmunogenSynthetic linear peptide corresponding to human Beta III Tubulin.
      HostRabbit
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Species Reactivity NoteDemonstrated to react with Rat. Predicted to react with Human and Mouse based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • TUBB3
      • TUBB4
      • MC1R
      • beta-4
      Purification MethodAffinity Purfied
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q13509 # Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.
      SIZE: 450 amino acids; 50433 Da
      SUBUNIT: Dimer of alpha and beta chains.
      DOMAIN:SwissProt: Q13509 The highly acidic C-terminal region may bind cations such as calcium.
      SIMILARITY: Belongs to the tubulin family.
      Molecular Weight50 kDa calculated
      Product Usage Statements
      Quality AssuranceEvaluated by Immunocytochemistry in rat E18 cortex cells.
      Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected Beta III Tubulin in rat E18 cortex cells.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Global Trade Item Number
      카탈로그 번호 GTIN
      AB15708C3 04053252537189