Anti-Alzheimer Precursor Protein A4 Antibody, clone 22C11, Biotin Conj. | MAB348B

Deposits of amyloid protein in senile plaques near nerve processes are found in the brains of aged humand and cases of Alzheimer′s Disease. The principle component of this extracellular amyloid is beta A4, a 4 kDa peptide derived from a larger amyloid precursor protein (APP), which is widely expressed in the brain and body. The creation, transport and function of these proteins is currently an active area of research.

Varies

Epitope: N-terminus

Purified recombinant Alzheimer precursor A4 (pre A4695) fusion protein

Evaluated by Immunohistochemistry in adult rat brain tissue.

Immunohistochemistry Analysis: A 1:100 dilution of this antibody detected Alzheimer Precursor Protein A4 in adult rat brain tissue.

Research Category
Neuroscience

Research Sub Category
Neurodegenerative Diseases

This antibody recognizes Alzheimer Precursor Protein A4 at the N-temrinus.

Protein A purified

Purified mouse monoclonal IgG1 conjugated to Biotin in PBS with 0.1% sodium azide and 15 mg/mL BSA.

Stable for 1 year at 2-8°C from date of receipt.

Control
Rat E18 primary cortex cells

Evaluated by Immunocytochemistry in rat E18 primary cortex cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected Alzheimer Precursor Protein A4 in rat E18 primary cortex cells.

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