175580
Angiogenesis Inhibitor
The Angiogenesis Inhibitor, also referenced under CAS 186611-44-9, controls the biological activity of Angiogenesis. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
동의어(들):
Angiogenesis Inhibitor, ( Z,E)-3-(Imidazol-4-ylmethylene)indolin-2-one, (Z,E)-3-(Imidazol-4-ylmethylene)indolin-2-one
조직 및 계약 가격을 보려면 로그인를 클릭합니다.
크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C12H9N3O
CAS 번호:
Molecular Weight:
211.22
MDL number:
NACRES:
NA.77
UNSPSC Code:
12352200
제품 이름
Angiogenesis Inhibitor, The Angiogenesis Inhibitor, also referenced under CAS 186611-44-9, controls the biological activity of Angiogenesis. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
assay
≥95% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
protect from light
color
yellow
solubility
DMSO: 5 mg/mL
shipped in
ambient
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
Cell permeable: yes
Primary Target
hEGF-R tyrosine kinase activity
hEGF-R tyrosine kinase activity
Product competes with ATP.
Reversible: no
Target IC50: 54% inhibition at 10 µM against hEGF-R tyrosine kinase activity
Disclaimer
Toxicity: Carcinogenic / Teratogenic (D)
Other Notes
Braud, E., et al. 2003. J. Enzyme Inhib. Med. Chem.18, 243.
Packaging
Packaged under inert gas
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
General description
A cell-permeable indolinone compound that displays anti-angiogenesis properties (30% inhibition of control at 10 µM in an in vitro rat aortic ring model ) with a potency that is comparable to that of SU5416 (Cat. No. 676487; 22% inhibition of control at 10 µM). Acts as a moderate ATP-competitive inhibitor of hEGF-R tyrosine kinase activity (54% inhibition at 10 µM).
저장 등급
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| 175580-10MGCN | 04055977222920 |
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.