Millipore Sigma Vibrant Logo

119137 Adenosine A2A Receptor Agonist I, CGS 21680, Hydrochloride - CAS 124182-57-6 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: CGS-21680, CGS21680, 3-(4-(2-((6-amino-9-((2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxytetrahydrofuran-2-yl)-9H-purin-2-yl)amino)ethyl)phenyl)propanoic acid

View Products on Sigmaaldrich.com
119137
가격 및 재고 조회

개요

가격 및 재고여부

카탈로그 번호 재고 정보패킹 포장 단위 가격(VAT 별도) 수량
119137-5MGCN
—
현재 재고 없음 현재 재고 없음
예상 출고 가능일 
단종품
제한된 수량 가능
재고여부 확인
    Remaining: will advise
      Remaining: will advise
      추천사항
      고객 서비스로 문의
      Contact Customer Service

      		 Glass bottle 5 mg
      가격을 검색할 수 없습니다
      Minimum Quantity needs to be mulitiple of
      Maximum Quantity is
      가격 문의 추가 정보
      ()이 할인됨
       
      —
      가격 문의
      		 —
      즐겨찾기에 추가
      Description
      OverviewA xanthin derivative that acts as a potent agonist of adenosine A2A receptors (Ki = 27 nM). Exhibits reduced affinity for A2B receptors (Ki = 67 nM), but offers greater selectivity over A1R (Ki = 290 nM) and A3R (88.8 µM). Exerts an anti-inflammatory effect during chronic inflammation and ameliorates the tissue damage associated with collagen-induced arthritis. Also shown to reduce CCR7 Protein Expression in THP1 macrophages. Shown to delay the progressive deterioration of motor performance and prevent a reduction in brain weight in murine model of Huntington's disease. Please note that the molecular weight for this compound is batch-specific due to variable water content. Please refer to the vial label or the certificate of analysis for the batch-specific molecular weight. The molecular weight provided represents the baseline molecular weight without water.
      Catalogue Number119137
      Brand Family Calbiochem®
      SynonymsCGS-21680, CGS21680, 3-(4-(2-((6-amino-9-((2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxytetrahydrofuran-2-yl)-9H-purin-2-yl)amino)ethyl)phenyl)propanoic acid
      References
      ReferencesWillians, A. J., et al. 2012. Inflammation. 35, 614.
      Mazzon, E. et al. 2011. J Rheumatol. 38, 2119,
      Martire, A., et al. 2007. Neurosci Lett. 417, 78.
      Chou, S. Y., et al, 2005. Journ Neurochem. 93, 310.
      Klotz, K. N., et al. 2000. Naunyn Schmiedebergs Arch Pharmacol.362 382.
      Phillis, J. W., et al. 1990.Brain Res. 509, 328.
      Product Information
      CAS number124182-57-6
      FormWhite solid
      FormulationSupplied as a hydrochloride salt.
      Hill FormulaC₂₃H₂₉N₇O₆ • HCl
      Chemical formulaC₂₃H₂₉N₇O₆ • HCl
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Purity≥96% by HPLC
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Global Trade Item Number
      카탈로그 번호 GTIN
      119137-5MGCN 04055977223330