수량	카탈로그 번호	주문 설명	포장 단위	기재 가격
			96-Well Plate

수량	카탈로그 번호	주문 설명	포장 단위	기재 가격
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

121765 Sigma-AldrichAG 825 - CAS 149092-50-2 - Calbiochem

A potent, cell-premeable, reversible, substrate competitive, and selective inhibitor of HER2 (neu/ErbB2; IC₅₀ = 0.35 µM) relative to HER1 (IC₅₀= 19 µM) autophosphorylation.

AG 825 - CAS 149092-50-2 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

SDS
CoA
References
Data Sheet

Synonyms: 4-Hydroxy-3-methoxy-5-(benzothiazolylthiomethyl)benzylidenecyanoacetamide

Primary Target: HER2

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개요

Replacement Information

주요 사양표

CAS #	Empirical Formula
149092-50-2	C₁₉H₁₅N₃O₃S₂

가격 및 재고여부

카탈로그 번호	재고 정보	패킹	포장 단위	가격(VAT 별도)	수량
121765-2MGCN	재고 정보 검색... — 현재 재고 없음 예상 출고 가능일 단종품 제한된 수량 가능 재고여부 확인 재고목록을 보려면 로그인하십시오 예상 출고 가능일 현재 재고 없음 예상 출고 가능일 Remaining: will advise Remaining: will advise 추천사항 고객 서비스로 문의 Contact Customer Service 고객 서비스로 문의 고객 서비스로 문의	Plastic ampoule	2 mg	가격 검색... 가격을 검색할 수 없습니다 Minimum Quantity needs to be mulitiple of Maximum Quantity is 가격 문의 추가 정보 ()이 할인됨 — 가격 문의 고객님의 가격을 보려면 로그인하십시오	재고 조회 —	즐겨찾기에 추가 즐겨찾기에 추가 나의 즐겨찾기에 추가

Description
Overview	A potent, cell-premeable, reversible, substrate competitive, and selective inhibitor of HER2 (neu/ErbB2; IC₅₀ = 0.35 µM) relative to HER1 (IC₅₀= 19 µM) autophosphorylation. The inhibition is competitive with respect to ATP binding. Enhances chemosensitivity in non-small cell lung cancer (NSCLC) cell lines expressing high levels of p185^neu.
Catalogue Number	121765
Brand Family	Calbiochem®
Synonyms	4-Hydroxy-3-methoxy-5-(benzothiazolylthiomethyl)benzylidenecyanoacetamide

References
References	Ashton, J.M., et al. 2012. Cell Stem Cell 11, 359. Tsai, C.M., et al. 1996. Cancer Res. 56, 1068. Levitzki, A., and Gazit, A. 1995. Science 267, 1782. Osherov, N., et al. 1993. J. Biol. Chem. 268, 11134.

Product Information
CAS number	149092-50-2
ATP Competitive	N
Form	Yellow solid
Hill Formula	C₁₉H₁₅N₃O₃S₂
Chemical formula	C₁₉H₁₅N₃O₃S₂
Reversible	Y
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Primary Target	HER2
Primary Target IC<sub>50</sub>	0.35 µM against HER2
Purity	≥94% by HPLC

Physicochemical Information
Cell permeable	Y

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	-20°C
Protect from Light	Protect from light
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2-3 months at -20°C.

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
카탈로그 번호	GTIN
121765-2MGCN	07790788047917

Documentation

AG 825 - CAS 149092-50-2 - Calbiochem MSDS

타이틀
물질안전보건자료(MSDS)

AG 825 - CAS 149092-50-2 - Calbiochem Certificates of Analysis

Title	Lot Number
121765	로트(lot) 번호를 입력하십시오.

References

참고문헌 보기
Ashton, J.M., et al. 2012. Cell Stem Cell 11, 359. Tsai, C.M., et al. 1996. Cancer Res. 56, 1068. Levitzki, A., and Gazit, A. 1995. Science 267, 1782. Osherov, N., et al. 1993. J. Biol. Chem. 268, 11134.

Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	24-March-2015 JSW
Synonyms	4-Hydroxy-3-methoxy-5-(benzothiazolylthiomethyl)benzylidenecyanoacetamide
Description	A potent, cell-premeable, reversible, substrate competitive, and selective inhibitor of HER-2 (neu/erbB-2, IC₅₀ = 0.35 µM) relative to HER-1 (IC₅₀ = 19 µM) autophosphorylation. The inhibition is competitive with respect to ATP binding. Enhances the chemosensitivity in non-small cell lung cancer (NSCLC) cell lines expressing high levels of p185^neu.
Form	Yellow solid
CAS number	149092-50-2
Chemical formula	C₁₉H₁₅N₃O₃S₂
Structure formula
Purity	≥94% by HPLC
Solubility	DMSO (10 mg/ml)
Storage	Protect from light -20°C
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2-3 months at -20°C.
Toxicity	Standard Handling
References	Ashton, J.M., et al. 2012. Cell Stem Cell 11, 359. Tsai, C.M., et al. 1996. Cancer Res. 56, 1068. Levitzki, A., and Gazit, A. 1995. Science 267, 1782. Osherov, N., et al. 1993. J. Biol. Chem. 268, 11134.

카테고리

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Protein Phosphorylation / Dephosphorylation > Protein Tyrosine Kinase (PTK) Inhibitors

해당 제품은 고객님의 카트에 추가되었습니다.