Millipore Sigma Vibrant Logo

100105 A23187, Free Acid, Streptomyces chartreusensis - CAS 52665-69-7 - Calbiochem

A mobile ion-carrier that forms stable complexes with divalent cations.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Calcimycin

View Products on Sigmaaldrich.com
100105
가격 및 재고 조회

개요

Replacement Information

주요 사양표

CAS #Empirical Formula
52665-69-7C₂₉H₃₇N₃O₆

가격 및 재고여부

카탈로그 번호 재고 정보패킹 포장 단위 가격(VAT 별도) 수량
100105-10MGCN
재고 정보 검색...
—
현재 재고 없음 현재 재고 없음
예상 출고 가능일 
단종품
제한된 수량 가능
재고여부 확인
    Remaining: will advise
      Remaining: will advise
      추천사항
      고객 서비스로 문의
      Contact Customer Service

      		 Plastic ampoule 10 mg
      가격 검색...
      가격을 검색할 수 없습니다
      Minimum Quantity needs to be mulitiple of
      Maximum Quantity is
      가격 문의 추가 정보
      ()이 할인됨
       
      —
      가격 문의
      		 —
      100105-1MGCN
      재고 정보 검색...
      —
      현재 재고 없음 현재 재고 없음
      예상 출고 가능일 
      단종품
      제한된 수량 가능
      재고여부 확인
        Remaining: will advise
          Remaining: will advise
          추천사항
          고객 서비스로 문의
          Contact Customer Service

          		 Plastic ampoule 1 mg
          가격 검색...
          가격을 검색할 수 없습니다
          Minimum Quantity needs to be mulitiple of
          Maximum Quantity is
          가격 문의 추가 정보
          ()이 할인됨
           
          —
          가격 문의
          		 —
          100105-5MGCN
          재고 정보 검색...
          —
          현재 재고 없음 현재 재고 없음
          예상 출고 가능일 
          단종품
          제한된 수량 가능
          재고여부 확인
            Remaining: will advise
              Remaining: will advise
              추천사항
              고객 서비스로 문의
              Contact Customer Service

              		 Plastic ampoule 5 mg
              가격 검색...
              가격을 검색할 수 없습니다
              Minimum Quantity needs to be mulitiple of
              Maximum Quantity is
              가격 문의 추가 정보
              ()이 할인됨
               
              —
              가격 문의
              		 —
              Description
              OverviewA mobile ion-carrier that forms stable complexes with divalent cations. Useful for increasing intracellular Ca2+ levels. Also acts as an uncoupler of oxidative phosphorylation and inhibitor of mitochondrial ATPase activity. An antibiotic with weak activity against Gram-positive bacteria. Also induces apoptosis in mouse lymphoma cell line (S49); however, A23187 has been shown to block apoptosis in other systems, such as when interleukin-3 (IL-3) is withdrawn from IL-3-dependent cells.
              Catalogue Number100105
              Brand Family Calbiochem®
              SynonymsCalcimycin
              References
              ReferencesCaron-Leslie, L.A., et al. 1994. FASEB J. 8, 639.
              Saunders, M.J., and Hepler, P.K. 1982. Science 217, 943.
              Pressman, B.C. 1976. Annu. Rev. Biochem. 45, 501.
              Pfeiffer, D.R., et al. 1974. Biochemistry 13, 4007.
              Reed, P.W., and Lardy, H.A. 1972. J. Biol. Chem. 247, 6970.
              Product Information
              CAS number52665-69-7
              ATP CompetitiveN
              FormWhite solid
              Hill FormulaC₂₉H₃₇N₃O₆
              Chemical formulaC₂₉H₃₇N₃O₆
              ReversibleN
              Structure formula ImageStructure formula Image
              Quality LevelMQ100
              Applications
              Biological Information
              Primary TargetMitochondrial ATPase
              Purity≥98% by TLC
              Physicochemical Information
              Cell permeableN
              Dimensions
              Materials Information
              Toxicological Information
              Safety Information according to GHS
              RTECSDM4676000
              Safety Information
              Product Usage Statements
              Storage and Shipping Information
              Ship Code Ambient Temperature Only
              Toxicity Standard Handling
              Storage +2°C to +8°C
              Protect from Light Protect from light
              Do not freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
              Packaging Information
              Transport Information
              Supplemental Information
              Specifications
              Global Trade Item Number
              카탈로그 번호 GTIN
              100105-10MGCN 04055977226232
              100105-1MGCN 04055977226225
              100105-5MGCN 04055977226249

              Documentation

              A23187, Free Acid, Streptomyces chartreusensis - CAS 52665-69-7 - Calbiochem MSDS

              타이틀

              물질안전보건자료(MSDS) 

              A23187, Free Acid, Streptomyces chartreusensis - CAS 52665-69-7 - Calbiochem Certificates of Analysis

              TitleLot Number
              100105

              References

              참고문헌 보기
              Caron-Leslie, L.A., et al. 1994. FASEB J. 8, 639.
              Saunders, M.J., and Hepler, P.K. 1982. Science 217, 943.
              Pressman, B.C. 1976. Annu. Rev. Biochem. 45, 501.
              Pfeiffer, D.R., et al. 1974. Biochemistry 13, 4007.
              Reed, P.W., and Lardy, H.A. 1972. J. Biol. Chem. 247, 6970.

              Brochure

              Title
              Caspases and other Apoptosis Related Tools Brochure
              Tools and Tips for Analyzing Apoptosis
              Data Sheet

              Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

              Revision07-April-2008 RFH
              SynonymsCalcimycin
              DescriptionA mobile ion-carrier that forms stable complexes with divalent cations. Useful for increasing intracellular Ca2+ levels. Also acts as an uncoupler of oxidative phosphorylation and inhibitor of mitochondrial ATPase activity. An antibiotic with weak activity against Gram positive bacteria. Also induces apoptosis in mouse lymphoma cell line (S49); however, A23187 has been shown to block apoptosis in other systems, such as when interleukin-3 (IL-3) is withdrawn from IL-3-dependent cells.
              FormWhite solid
              CAS number52665-69-7
              RTECSDM4676000
              Chemical formulaC₂₉H₃₇N₃O₆
              Structure formulaStructure formula
              Purity≥98% by TLC
              SolubilityDMSO or Methanol. For use in aqueous systems, preparation of a 100 mM stock in DMSO is recommended. Microliter amounts of this solution can then be added to H₂O with rapid mixing (e.g. 10 µl into 5 ml of H₂O). In aqueous systems, the ionophore aggregates over time.
              Storage Protect from light
              +2°C to +8°C
              Do Not Freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
              Toxicity Standard Handling
              Merck USA index14, 1639
              ReferencesCaron-Leslie, L.A., et al. 1994. FASEB J. 8, 639.
              Saunders, M.J., and Hepler, P.K. 1982. Science 217, 943.
              Pressman, B.C. 1976. Annu. Rev. Biochem. 45, 501.
              Pfeiffer, D.R., et al. 1974. Biochemistry 13, 4007.
              Reed, P.W., and Lardy, H.A. 1972. J. Biol. Chem. 247, 6970.

              관련 제품 및 어플리케이션

              Alternative Products

              카탈로그 번호 설명  
              100106 A23187, Mixed Calcium-Magnesium Salt - CAS 52665-69-7 - Calbiochem 가격 및 재고 조회
              100107 A23187, 4-Bromo- - CAS 76455-48-6 - Calbiochem 가격 및 재고 조회

              Related Products

              카탈로그 번호 설명  
              407950 Ionomycin, Free Acid, Streptomyces conglobatus - CAS 56092-81-0 - Calbiochem 가격 및 재고 조회

              카테고리

              Life Science Research > Inhibitors and Biochemicals > Biochemicals > Ionophores