565789 Sigma-Aldrichγ-Secretase Inhibitor XX - CAS 209984-56-5 - Calbiochem
This γ-secretase inhibitor, CAS 209984-56-5, is a cell-permeable dibenzazepine compound that lowers both brain and plasma Aβ40 levels by ~72% in Tg2576 mutant APP transgenic mouse model.
More>> This γ-secretase inhibitor, CAS 209984-56-5, is a cell-permeable dibenzazepine compound that lowers both brain and plasma Aβ40 levels by ~72% in Tg2576 mutant APP transgenic mouse model. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: (S,S)-2-[2-(3,5-Difluorophenyl)acetylamino]-N-(5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)propionamide, DBZ, Dibenzazepine
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개요
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주요 사양표
| CAS # | Empirical Formula |
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| 209984-56-5 | C₂₆H₂₃F₂N₃O₃ |
가격 및 재고여부
| 카탈로그 번호 | 재고 정보 | 패킹 | 포장 단위 | 가격(VAT 별도) | 수량 | |
|---|---|---|---|---|---|---|
| 565789-1MGCN |
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Glass bottle | 1 mg |
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| 565789-500UGCN |
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Plastic ampoule | 500 μg |
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| References | |
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| References | Droy-Dupré, L., et al. 2012. Dis. Model Mech. 5, 107. van Es, J.H., et al. 2005. Nature 435, 959. Milano, J., et al. 2004. Toxicol. Sci. 82, 341. |
| Product Information | |
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| CAS number | 209984-56-5 |
| ATP Competitive | N |
| Form | White solid |
| Hill Formula | C₂₆H₂₃F₂N₃O₃ |
| Chemical formula | C₂₆H₂₃F₂N₃O₃ |
| Reversible | N |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
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| Biological Information | |
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| Primary Target | γ-secretase |
| Primary Target IC<sub>50</sub> | 1.7 nM inhibiting Notch processing in SupT1 cells |
| Purity | ≥95% by HPLC |
| Physicochemical Information | |
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| Cell permeable | Y |
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| Materials Information |
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| Toxicological Information |
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| Safety Information |
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| Product Usage Statements |
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| Packaging Information | |
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| Packaged under inert gas | Packaged under inert gas |
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| Specifications |
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| Global Trade Item Number | |
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| 카탈로그 번호 | GTIN |
| 565789-1MGCN | 04055977191837 |
| 565789-500UGCN | 04055977191844 |
Documentation
γ-Secretase Inhibitor XX - CAS 209984-56-5 - Calbiochem MSDS
| 타이틀 |
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γ-Secretase Inhibitor XX - CAS 209984-56-5 - Calbiochem Certificates of Analysis
| Title | Lot Number |
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| 565789 |
References
| 참고문헌 보기 |
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| Droy-Dupré, L., et al. 2012. Dis. Model Mech. 5, 107. van Es, J.H., et al. 2005. Nature 435, 959. Milano, J., et al. 2004. Toxicol. Sci. 82, 341. |
Citations
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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