Millipore Sigma Vibrant Logo

565761 γ-Secretase Inhibitor IV - Calbiochem

The γ-Secretase Inhibitor IV controls the biological activity of γ-Secretase. This small molecule/inhibitor is primarily used for Neuroscience applications.

γ-Secretase Inhibitor IV - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 2-Naphthoyl-VF-CHO, N-(2-Naphthoyl)-Val-phenylalaninal

Primary Target: Aβx-40
View Products on Sigmaaldrich.com
565761
가격 및 재고 조회

개요

Replacement Information

주요 사양표

Empirical Formula
C₂₅H₂₆N₂O₃

가격 및 재고여부

카탈로그 번호 재고 정보패킹 포장 단위 가격(VAT 별도) 수량
565761-1MGCN
재고 정보 검색...
—
현재 재고 없음 현재 재고 없음
예상 출고 가능일 
단종품
제한된 수량 가능
재고여부 확인
    Remaining: will advise
      Remaining: will advise
      추천사항
      고객 서비스로 문의
      Contact Customer Service

      		 Plastic ampoule 1 mg
      가격 검색...
      가격을 검색할 수 없습니다
      Minimum Quantity needs to be mulitiple of
      Maximum Quantity is
      가격 문의 추가 정보
      ()이 할인됨
       
      —
      가격 문의
      		 —
      Description
      OverviewA cell-permeable, reversible inhibitor of γ-secretase. Equipotently inhibits the release of Aβx-40 (ED50 = 2.6 µM) and Aβx-42 (ED50 = 2.7 µM) in HEK293 cells stably transfected with the Amyloid Precursor Protein Swedish mutants.
      Catalogue Number565761
      Brand Family Calbiochem®
      Synonyms2-Naphthoyl-VF-CHO, N-(2-Naphthoyl)-Val-phenylalaninal
      References
      ReferencesGreen, K.N., et al. 2002. J. Physiol. 541.3, 1013.
      Sinha, S. and Lieberburg, I. 1999. Proc. Natl. Acad. Sci. USA 96, 11049.
      Product Information
      ATP CompetitiveN
      FormWhite lyophilized solid
      Hill FormulaC₂₅H₂₆N₂O₃
      Chemical formulaC₂₅H₂₆N₂O₃
      ReversibleY
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetAβx-40
      Primary Target IC<sub>50</sub>ED50 = 2.6 µM for Aβx-40
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableY
      Peptide Sequence2-Naphthoyl-Val-Phe-CHO
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      카탈로그 번호 GTIN
      565761-1MGCN 04055977267716

      Documentation

      γ-Secretase Inhibitor IV - Calbiochem MSDS

      타이틀

      물질안전보건자료(MSDS) 

      γ-Secretase Inhibitor IV - Calbiochem Certificates of Analysis

      TitleLot Number
      565761

      References

      참고문헌 보기
      Green, K.N., et al. 2002. J. Physiol. 541.3, 1013.
      Sinha, S. and Lieberburg, I. 1999. Proc. Natl. Acad. Sci. USA 96, 11049.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision10-September-2008 RFH
      Synonyms2-Naphthoyl-VF-CHO, N-(2-Naphthoyl)-Val-phenylalaninal
      DescriptionA cell-permeable, reversible inhibitor of γ-secretase. Inhibits the release of Aβx-40 (ED50 = 2.6 µM) and Aβx-42 (ED50 = 2.7 µM) in HEK293 cells stably transfected with Amyloid Precursor Protein Swedish mutants.
      FormWhite lyophilized solid
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₂₅H₂₆N₂O₃
      Peptide Sequence2-Naphthoyl-Val-Phe-CHO
      Purity≥95% by HPLC
      SolubilityDMSO (10 mg/ml)
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesGreen, K.N., et al. 2002. J. Physiol. 541.3, 1013.
      Sinha, S. and Lieberburg, I. 1999. Proc. Natl. Acad. Sci. USA 96, 11049.