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324355 n-Dodecyl-β-D-maltoside, ULTROL® Grade - CAS 69227-93-6 - Calbiochem

CAS 69227-93-6 is a non-ionic detergent similar to n-octyl-β-D-glucopyranoside; however, increased alkyl chain length has been shown to increase thermal stability of lipid-free rhodopsin in solution.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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324355
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Overview

Replacement Information

Key Spec Table

CAS #
69227-93-6

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      324355-1GMCN
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          324355-25GMCN
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              324355-5GMCN
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                  Description
                  OverviewNon-ionic detergent similar to n-octyl-β-D-glucopyranoside; however, increased alkyl chain length has been shown to increase thermal stability of lipid-free rhodopsin in solution. Useful in membrane-protein solubilization studies. Aggregation number: 98.
                  Absorbance (10%, H2O, 260 nm): <1.0.
                  Catalogue Number324355
                  Brand Family Calbiochem®
                  References
                  ReferencesWitzmann, F., et al. 1991. Electrophoresis 12, 687.
                  Bass, W.T., and Bricker, T.M. 1988. Anal. Biochem. 171, 330.
                  Rosevear, P., et al. 1980. Biochemistry 19, 4108.
                  Grip, W.J., and Bovee-Geurts, P.H.M. 1979. Chem. Phys. Lipids 23, 321.
                  Stubbs, G.W., et al. 1976. Biochim. Biophys. Acta 425, 46.
                  Product Information
                  CAS number69227-93-6
                  Aggregation Number98
                  CMC100-600 µM
                  FormWhite solid
                  Hygroscopic Hygroscopic
                  Micellar weight50000
                  Structure formula ImageStructure formula Image
                  Quality LevelMQ100
                  Applications
                  Biological Information
                  Purity≥98% by HPLC
                  Physicochemical Information
                  Contaminantsdodecanol 1H NMR: ≤1%
                  Dimensions
                  Materials Information
                  Toxicological Information
                  Safety Information according to GHS
                  Safety Information
                  Product Usage Statements
                  Storage and Shipping Information
                  Ship Code Ambient Temperature Only
                  Toxicity Standard Handling
                  Storage +2°C to +8°C
                  Hygroscopic Hygroscopic
                  Do not freeze Ok to freeze
                  Special InstructionsFollowing reconstitution, refrigerate (4°C).
                  Stock solutions are stable for up to 3 months at 4°C.
                  Packaging Information
                  Transport Information
                  Supplemental Information
                  Specifications
                  Global Trade Item Number
                  Catalogue Number GTIN
                  324355-100GMCN 04055977216417
                  324355-1GMCN 07790788054175
                  324355-25GMCN 04055977216424
                  324355-5GMCN 04055977216448

                  Documentation

                  n-Dodecyl-β-D-maltoside, ULTROL® Grade - CAS 69227-93-6 - Calbiochem SDS

                  Title

                  Safety Data Sheet (SDS) 

                  n-Dodecyl-β-D-maltoside, ULTROL® Grade - CAS 69227-93-6 - Calbiochem Certificates of Analysis

                  TitleLot Number
                  324355

                  References

                  Reference overview
                  Witzmann, F., et al. 1991. Electrophoresis 12, 687.
                  Bass, W.T., and Bricker, T.M. 1988. Anal. Biochem. 171, 330.
                  Rosevear, P., et al. 1980. Biochemistry 19, 4108.
                  Grip, W.J., and Bovee-Geurts, P.H.M. 1979. Chem. Phys. Lipids 23, 321.
                  Stubbs, G.W., et al. 1976. Biochim. Biophys. Acta 425, 46.

                  Brochure

                  Title
                  Biological Detergents Brochure
                  CALBIOSORBﾙ Technical Bulletin

                  Citations

                  Title
                • Serban P. Georgescu, et al. (2005) Modulator recognition factor 1 (MRF1), an ARID-family member, is a novel co-repressor for estrogen receptor α. Molecular Endocrinology 19, 2491-2501.
                  		•
                  Data Sheet

                  Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

                  Revision20-December-2010 JSW
                  DescriptionA water-soluble nonionic detergent. Studies on rhodopsin have shown that alkyl glycosides with longer alkyl chains are better at preserving the protein's properties. In addition, dodecyl maltoside's longer hydrophilic group confers higher solubility in water. This is in contrast to undecyl and dodecyl glucosides, which have low solubility in water. Due to its low CMC, dodecyl maltoside is not easily removed by dialysis. The half time for dialysis is 20 h. This detergent is milder than nonyl glucoside. Of several glycosides tested, dodecyl maltoside was found to be the most useful for the preparation of active cytochrome oxidase from Neurospora. In octyl glucoside, cytochrome oxidase dissociated into its subunits and became inactive. Similarly, beef heart oxidase when equilibrated in octyl glucoside formed a mixture of polymer, dimer, and lower molecular weight forms and underwent denaturation. In contrast, the enzyme, when equilibrated in dodecyl maltoside, was found to exist as a uniform species of 30 kDa, which is consistent with an active dimeric form. Dodecyl maltoside has a critical micelle concentration (CMC) of 100-600 µM and a micellar weight of 70,000. Aggregation number: 98.
                  FormWhite solid
                  CAS number69227-93-6
                  Structure formulaStructure formula
                  Purity≥98% by HPLC
                  Contaminantsdodecanol 1H NMR: ≤1%
                  SolubilityH₂O (100 mg/ml)
                  Storage +2°C to +8°C
                  Hygroscopic
                  Do Not Freeze Ok to freeze
                  Special InstructionsFollowing reconstitution, refrigerate (4°C).
                  Stock solutions are stable for up to 3 months at 4°C.
                  Toxicity Standard Handling
                  ReferencesWitzmann, F., et al. 1991. Electrophoresis 12, 687.
                  Bass, W.T., and Bricker, T.M. 1988. Anal. Biochem. 171, 330.
                  Rosevear, P., et al. 1980. Biochemistry 19, 4108.
                  Grip, W.J., and Bovee-Geurts, P.H.M. 1979. Chem. Phys. Lipids 23, 321.
                  Stubbs, G.W., et al. 1976. Biochim. Biophys. Acta 425, 46.
                  Citation
                • Serban P. Georgescu, et al. (2005) Modulator recognition factor 1 (MRF1), an ARID-family member, is a novel co-repressor for estrogen receptor α. Molecular Endocrinology 19, 2491-2501.
                  		•