Skip to Content
Merck

8.01663

Boron trifluoride-methanol complex

(20% solution in methanol) for synthesis

Synonym(s):

BF3 methanol

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

NACRES:
NA.22
UNSPSC Code:
12352301
Assay:
14.0-16.0%
Grade:
synthesis grade
Vapor pressure:
4 hPa ( 20 °C)

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

grade

synthesis grade

vapor pressure

4 hPa ( 20 °C)

assay

14.0-16.0%

form

liquid

autoignition temp.

420 °C

expl. lim.

5.5 % (v/v) Methanol)

dilution

(for synthesis)

transition temp

flash point 16 °C

density

0.89 g/cm3 at 20 °C

storage temp.

2-30°C

Quality Level

200

General description

Boron trifluoride-methanol complex (BF-M) is Lewis acid boron trifluoride incoordination with methanol. BF-M is a powerful acidic catalyst for the esterification of fatty acids. In the deacetylation of acetanilides, the complex displayed excellent deprotection selectivity against amino-protecting groups.

Application

Boron trifluoride-methanol complex is used:
  • As a reagent for deprotection of N-acetyl derivatives (acetylated amines of cyanine-type dyes).
  • As a starting material in the automated radiosynthesis procedure for [18F]tetrafluoroborate.

Analysis Note

Assay BF3 (acidimetric): 14.0 - 16.0 %
Density (d 20 °C/ 4 °C): 0.880 - 0.895

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 1

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

60.8 °F

flash_point_c

16 °C

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Boron trifluoride--methanol complex-mild and powerful reagent for deprotection of labile acetylated amines
Miltsov S, et al.
Tetrahedron Letters, 44(11), 2301-2303 (2003)
Comparison of transesterification methods for production of biodiesel from vegetable oils and fats
Demirbas A
Energy Conversion and Management , 49(1), 125-130 (2008)
High molar activity [18F] tetrafluoroborate synthesis for sodium iodide symporter imaging by PET
Soloviev D, et al.
EJNMMI radiopharmacy and chemistry, 7(1), 1-17 (2022)
Boron trifluoride--methanol complex. Mild and powerful reagent for deprotection of acetylated amines. Scope and selectivity
Miltsov S, et al.
Tetrahedron Letters, 57(6), 641-644 (2016)

Global Trade Item Number

SKUGTIN
8.01663.050004022536369570
8.01663.010004022536369563

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service