Skip to Content
Merck

1.52025

Chromolith® HighResolution RP-18 endcapped (monolithic) HPLC Columns

L × I.D. 5 mm x 4.6 mm Guard Cartridges (3 pieces)

Synonym(s):

Chromolith® HighResolution RP-18 endcapped 5-4.6 guard cartridges (3 pieces)

Sign In to View Organizational & Contract Pricing.

Select a Size


About This Item

UNSPSC Code:
41115709
NACRES:
SB.52
Matrix active group:
C18 bonding phase, octadecylsilane (ODS), C18 bonding phase
Pore size:
1.15 μm macroporosity, 1.5 μm macroporosity
Matrix:
highly porous
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Chromolith® HighResolution RP-18 endcapped, L × I.D. 5 mm x 4.6 mm guard cartridges (3 pieces)

material

PEEK column

agency

suitable for ISO/CEN 6304.09, suitable for USP L1

product line

Chromolith®

Quality Level

packaging

pkg of 3 ea

extent of labeling

15% Carbon loading

parameter

400 bar pressure, 45 °C max. temp., 50 °C max. temp.

technique(s)

LC/MS: suitable

column L × I.D.

0.5 cm × 4.6 mm

surface area

250 m2/g × 250 m2/g

matrix

highly porous

matrix active group

C18 bonding phase, octadecylsilane (ODS), C18 bonding phase

pore size

1.15 μm macroporosity, 1.5 μm macroporosity

application(s)

PFAS testing

separation technique

reversed phase

storage temp.

no temp limit

Looking for similar products? Visit Product Comparison Guide

General description

Although the Chromolith® columns are well known for their robustness and longevity, guard columns are available to prolong the lifespan of Chromolith® analytical columns even further. These guard cartridges require a special holder.

Chromolith® HighResolution RP-18 endcapped 5-4.6 guard cartridges are extremely easy to use. The guard cartridges are simply added directly in front of the main column to protect it from chemical or mechanical contamination. Due to the benefits of monolithic technology, and the convenience of Chromolith® guard columns, they are also popular for use with classical particulate columns. Moreover, guard columns can be used as trap columns when large sample volumes are to be injected. Guard columns should be changed frequently in order to avoid excessive accumulation of impurities.

Chromolith® columns are made of monolithic silica with a characteristic bimodal pore structure.

Chromolith® HighResolution RP-18 endcapped 5-4.6 guard cartridges are used with the Chromolith® Guard Cartridge Holder 5 mm x 4.6 mm [1.52032]

Learn more:
Brochure: Race through your Separations on Any System. Chromolith® Monolithic Silica HPLC Columns

All Supelco HPLC Columns, including monolithic Chromolith® columns, are fully compatible to all HPLC and UHPLC Instruments.
Supelco HPLC Products: The Best Choice for Any LC Instrument

Application


  • A Novel and Sensitive LC-MS/MS Method for the Quantitation of Ceftiofur in Pharmaceutical Preparations and Milk Samples.: This study, conducted by Levent S, Özcan S, Geven A, and Can NÖ, presents a new LC-MS/MS method utilizing Chromolith® HighResolution RP-18 endcapped columns. The method provides high sensitivity and specificity for the quantitation of ceftiofur, a veterinary antibiotic, in both pharmaceutical preparations and milk samples, demonstrating its potential for robust analytical applications in pharmaceutical and food safety contexts (Levent et al., 2021).

Legal Information

Chromolith is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Articles

Monolithic silica HPLC columns enable high-throughput analysis at low back pressure without loss of separation efficiency or peak capacity.

Related Content

Discover our complete solutions: Reliable products and precision tools to more accurately quantify PFAS compounds in diverse samples including water, wastewater, soil, food, blood, etc.

전체 솔루션을 알아보세요. 신뢰할 수 있는 제품과 정밀한 툴로 물, 폐수, 흙, 식품, 혈액 등이 포함된 다양한 샘플에서 PFAS 화합물의 양을 더욱 정확하게 측정할 수 있습니다.

See All

Global Trade Item Number

SKUGTIN
1.52025.000104027269204877

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service