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05-23-0111 [Tyr(PO₃H₂)⁴]-Angiotensin II, Human - Calbiochem

Shown to inhibit renin release in a mean arterial pressure assay with similar potency to angiotensin II amide.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: DRVpYIHPF

Primary Target: Inhibit renin release in a mean arterial pressure assay
05-23-0111
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₅₀H₇₂N₁₃O₁₅P

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      		 Plastic ampoule 5 mg
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      Description
      OverviewShown to inhibit renin release in a mean arterial pressure assay with similar potency to angiotensin II amide. However, it has a longer duration of action that is attributed to either stronger binding to the angiotensin II receptor or slower degradation by recirculating peptidases.
      Catalogue Number05-23-0111
      Brand Family Calbiochem®
      SynonymsDRVpYIHPF
      References
      ReferencesShin, Y.A., and Yoo, S.E. 1996. Biopolymers 38, 183.
      Kitas, E.A., et al. 1993. Peptide Res. 6, 205.
      Product Information
      ATP CompetitiveN
      FormSolid
      FormulationSupplied as a trifluoroactate salt.
      Hill FormulaC₅₀H₇₂N₁₃O₁₅P
      Chemical formulaC₅₀H₇₂N₁₃O₁₅P
      Hygroscopic Hygroscopic
      ReversibleN
      Sold on the basis of peptide contentY
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetInhibit renin release in a mean arterial pressure assay
      Purity≥97% by HPLC
      Physicochemical Information
      Cell permeableN
      Peptide ContentY
      Peptide SequenceH-Asp-Arg-Val-Tyr(PO₃H₂)-Ile-His-Pro-Phe-OH
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      05230111-5MGCN 04055977206937

      Documentation

      [Tyr(PO₃H₂)⁴]-Angiotensin II, Human - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      [Tyr(PO₃H₂)⁴]-Angiotensin II, Human - Calbiochem Certificates of Analysis

      TitleLot Number
      05-23-0111

      References

      Reference overview
      Shin, Y.A., and Yoo, S.E. 1996. Biopolymers 38, 183.
      Kitas, E.A., et al. 1993. Peptide Res. 6, 205.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision18-September-2008 RFH
      SynonymsDRVpYIHPF
      DescriptionShown to inhibit renin release in a mean arterial pressure assay with similar potency to angiotensin II amide; however, it has a longer duration of action, which is attributed to either stronger binding to the angiotensin II receptor or slower degradation by recirculating peptidases.
      FormSolid
      FormulationSupplied as a trifluoroactate salt.
      Chemical formulaC₅₀H₇₂N₁₃O₁₅P
      Peptide SequenceH-Asp-Arg-Val-Tyr(PO₃H₂)-Ile-His-Pro-Phe-OH
      Purity≥97% by HPLC
      Solubility5% Acetic Acid (1 mg/ml)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesShin, Y.A., and Yoo, S.E. 1996. Biopolymers 38, 183.
      Kitas, E.A., et al. 1993. Peptide Res. 6, 205.