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GF180 MIF,
Human Recombinant

MIF,
Human Recombinant MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
UniProt Number: P14174
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GF180
25µg  
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      Overview

      Replacement Information

      Key Spec Table

      SourcePurity
      Protein is expressed in insect cells.Product endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
      Description
      Catalogue NumberGF180
      DescriptionMIF,
      Human Recombinant
      Alternate Names
      • Macrophage Migration Inhibitory Factor
      Background InformationMacrophage Migration Inhibitory Factor (MIF) is a small secreted protein that can act as a pleiotropic pro-inflammatory cytokine as well as an enzyme. MIF pro-inflammatory activity can be initiated by signaling through CD74 and CD44, resulting in the secretion of TNF-a, IL-1, IL-6, IL-8, and various MMPs. The enzymatic activity of MIF is characterized by its ability to act as a tautomerase, capable of catalyzing the keto to enol isomerization of keto-phenylpyruvate and L-dopachrome. It appears as though MIF catalytic activity is dependent upon a trimeric configuration and a free N-terminal proline residue.
      Insect cell derived recombinant MIF is a 15 kDa protein containing 124 amino acid residues, including an N-terminal His-tag.
      References
      Product Information
      PresentationProduct is presented in 10mM Sodium Citrate, pH 3.0 and is filtered through a 0.2 micron filter before lyophilization.
      Quality LevelMQ100
      Applications
      Biological Information
      PurityProduct endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
      SourceProtein is expressed in insect cells.
      UniProt Number
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceDetermined by its ability to inhibit monocyte migration.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore at -20°C for up to 4 months from date of receipt Centrifuge the vial prior to opening.
      Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein and store in working aliquots at -20°C.
      Packaging Information
      Material Size25µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      GF180 04053252979569

      Documentation

      MIF,
      Human Recombinant SDS

      Title

      Safety Data Sheet (SDS) 

      MIF,
      Human Recombinant Certificates of Analysis

      TitleLot Number
      MIF, Human Recombinant - Q2449363 Q2449363
      MIF, -2734731 2734731
      MIF, Human Recombinant - 2986021 2986021
      MIF, Human Recombinant - 3232378 3232378
      MIF, Human Recombinant - 3288746 3288746
      MIF, Human Recombinant - 3537170 3537170
      MIF, Human Recombinant - 3900431 3900431
      MIF, Human Recombinant - 3979881 3979881
      MIF, Human Recombinant Recombinant Protein 3040378
      MIF, Human Recombinant Recombinant Protein 2967197
      Show more

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      Categories

      Life Science Research > Proteins and Enzymes > Cytokines & Growth Factors
      Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Cytokines & Growth Factors