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420318 Kainic Acid - CAS 487-79-6 - Calbiochem

An excitatory amino acid receptor agonist selective for the kainate receptor subtype (Ki = 21 nM for ³H-kainate binding in rat striatum).

Kainic Acid - CAS 487-79-6 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic Acid

Primary Target: Kainate receptor subtype
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420318
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
487-79-6C₁₀H₁₅NO₄

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420318-10MGCN
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      Description
      OverviewAn excitatory amino acid receptor agonist selective for the kainate receptor subtype (Ki = 21 nM for 3H-kainate binding in rat striatum). Also activates AMPA receptors.
      Catalogue Number420318
      Brand Family Calbiochem®
      Synonyms2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic Acid
      References
      ReferencesNiu, L., et al. 1996. Biochemistry 35, 2030.
      Watkins, J.C. and Evans, R.H. 1981. Annu. Rev. Pharmacol. Toxicol. 21, 165.
      Product Information
      CAS number487-79-6
      ATP CompetitiveN
      FormOff-white solid
      Hill FormulaC₁₀H₁₅NO₄
      Chemical formulaC₁₀H₁₅NO₄
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ200
      Applications
      Biological Information
      Primary TargetKainate receptor subtype
      Primary Target K<sub>i</sub>21 nM for 3H-kainate binding in rat striatum
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSUX9665250
      Safety Information
      R PhraseR: 20/21/22

      Harmful by inhalation, in contact with skin and if swallowed.
      S PhraseS: 36

      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      420318-10MGCN 04055977211016

      Documentation

      Kainic Acid - CAS 487-79-6 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Kainic Acid - CAS 487-79-6 - Calbiochem Certificates of Analysis

      TitleLot Number
      420318

      References

      Reference overview
      Niu, L., et al. 1996. Biochemistry 35, 2030.
      Watkins, J.C. and Evans, R.H. 1981. Annu. Rev. Pharmacol. Toxicol. 21, 165.

      Brochure

      Title
      Pathways and Biomarkers of Glutamatergic Synapse Flyer
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision13-May-2008 RFH
      Synonyms2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic Acid
      DescriptionAn excitatory amino acid receptor agonist selective for the kainate receptor subtype (Ki = 21 nM for 3H-kainate binding in rat striatum). Also activates AMPA receptors.
      FormOff-white solid
      CAS number487-79-6
      RTECSUX9665250
      Chemical formulaC₁₀H₁₅NO₄
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityH₂O (10 mg/ml) or dilute base (10 mg/ml)
      Storage +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Toxicity Harmful
      Merck USA index14, 5276
      ReferencesNiu, L., et al. 1996. Biochemistry 35, 2030.
      Watkins, J.C. and Evans, R.H. 1981. Annu. Rev. Pharmacol. Toxicol. 21, 165.