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234599 Conduritol B Epoxide - CAS 6090-95-5 - Calbiochem

Conduritol B Epoxide, CAS 6090-95-5, is an irreversible Inhibitor of glucocerebrosidase in neurons. Also inhibits α-glucosidase activity in a variety of species.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: CBE, 1,2-Anhydro-myo-inositol

Primary Target: α-glucosidase
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234599
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
6090-95-5C₆H₁₀O₅

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234599-100MGCN
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      		 Glass bottle 100 mg
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      Description
      OverviewInhibits α-glucosidase activity in mammals, snails, sweet almonds, and yeast. An irreversible, potent, and specific inhibitor of glucocerebrosidase in cultured neurons. Has also been shown to inhibit α-glucosidase from yeast and rabbit intestinal sucrase-isomaltase complex.
      Catalogue Number234599
      Brand Family Calbiochem®
      SynonymsCBE, 1,2-Anhydro-myo-inositol
      References
      ReferencesKorkotian, E., et al. 1999. J. Biol. Chem. 274, 21673.
      Ogawa, S., et al. 1999. Bioorg. Med. Chem. 9, 1493.
      Hermans, M.M., et al. 1991. J. Biol. Chem. 266, 13507.
      Product Information
      CAS number6090-95-5
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₆H₁₀O₅
      Chemical formulaC₆H₁₀O₅
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetα-glucosidase
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 20/21/22

      Harmful by inhalation, in contact with skin and if swallowed.
      S PhraseS: 36

      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful
      Storage -20°C
      Protect from Moisture Protect from moisture
      Do not freeze Ok to freeze
      Special InstructionsUnstable in solution; reconstitute just prior to use.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      234599-100MGCN 07790788059569

      Documentation

      Conduritol B Epoxide - CAS 6090-95-5 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Conduritol B Epoxide - CAS 6090-95-5 - Calbiochem Certificates of Analysis

      TitleLot Number
      234599

      References

      Reference overview
      Korkotian, E., et al. 1999. J. Biol. Chem. 274, 21673.
      Ogawa, S., et al. 1999. Bioorg. Med. Chem. 9, 1493.
      Hermans, M.M., et al. 1991. J. Biol. Chem. 266, 13507.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision18-June-2013 JSW
      SynonymsCBE, 1,2-Anhydro-myo-inositol
      DescriptionInhibits α-glucosidase activity in mammals, snails, sweet almonds and yeast. An irreversible, potent, and specific inhibitor of glucocerebrosidase in cultured neurons. Has also been shown to inhibit α-glucosidase from yeast, and rabbit intestinal sucrase-isomaltase complex.
      FormWhite solid
      CAS number6090-95-5
      Chemical formulaC₆H₁₀O₅
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityDMSO or H₂O
      Storage Protect from moisture
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsUnstable in solution; reconstitute just prior to use.
      Toxicity Harmful
      ReferencesKorkotian, E., et al. 1999. J. Biol. Chem. 274, 21673.
      Ogawa, S., et al. 1999. Bioorg. Med. Chem. 9, 1493.
      Hermans, M.M., et al. 1991. J. Biol. Chem. 266, 13507.