Cogent® Process-Scale Tangential Flow Filtration System
A fully-automated, configurable, TFF system suited for manufacturing of biopharmaceuticals and cGMP process-scale applications
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Overview
The fully automated Cogent® TFF system is designed to separate and purify monoclonal antibodies, vaccines, plasma, and therapeutic proteins. It is ideally suited for both pilot and production scale applications, thereby supporting rapid scale up from small to large scale operations.
Benefiting from our leading bioprocess knowledge and engineering expertise, the Cogent® Process Scale System is the culmination of 25 years of custom system design and incorporates many unique, innovative and intelligent design features. This system has a very low hold-up volume for maximum volume concentration and optimal product recovery, thus enhancing process performance.
Benefits:
- Modular standard options allow the unique system configuration that best matches process requirements while minimizing upfront investment.
- Full process automation eases the consistent production of preclinical and clinical scale quantities of high-value drug products to cGMP standard.
- Optimized design and component integration of NovAseptic® valves and TFF cassette holders result in a low minimum working volume and ensure maximum product recovery.
- Designed to maximize TFF performances in fed-batch, concentration, total recycle or single pass mode.
- Comprehensive services ensure rapid implementation and optimized performance.
