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MABF276 Anti-S100A9/MRP14 Antibody, clone 17

This Anti-S100A9/MRP14 Antibody, clone 17 is validated for use in Western Blotting and Flow Cytometry for the detection of S100A9/MRP14.

Anti-S100A9/MRP14 Antibody, clone 17 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology Gene Symbol: S100A9, CAGB, CFAG, MRP14 UniProt Number: P06702
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MABF276
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, FCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABF276
      DescriptionAnti-S100A9/MRP14 Antibody, clone 17
      Alternate Names
      • Protein S100-A9
      • Calgranulin-B
      • Calprotectin L1H subunit
      • Leukocyte L1 complex heavy chain
      • Migration inhibitory factor-related protein 14
      • MRP-14
      • p14
      • S100 calcium-binding protein A9
      Background InformationS100A8, also known as Protein S100-A8, Calgranulin-A, Calprotectin L1L subunit, Cystic fibrosis antigen (CFAG), Leukocyte L1 complex light chain, Migration inhibitory factor related protein 8 (MRP-14), p8, S100 calcium binding protein A8, or Urinary stone protein band A, and encoded by the gene S100A8/CAGA/CFAG/MRP14, is an important protein that binds both zinc and calcium and plays an important role in the regulation of inflammatory processes and immune response. Found in complex with its partner S100A9, S100A8 facilitates chemotaxis, fatty acid trafficking, cytoskeleton reorganization, and NAPDPH oxidase activation and other intracellular activities, as well as a host of extracellular induced activities such as extracellular proinflammatory, antimicrobial, oxidant scavenging, and apoptotic activities . Additionally S100A8 can act as a potent autoimmunity amplifier and appears to augment various cancers and their spread when over expressed. S100A8 is widely expressed and used as biomarker in patients with inflammatory diseases and as a cancer marker in multiple forms of cancer.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-S100A9/MRP14 Antibody, clone 17 is validated for use in Western Blotting and Flow Cytometry for the detection of S100A9/MRP14.
      Key Applications
      • Western Blotting
      • Flow Cytometry
      Application NotesFlow Cytometry Analysis: 0.5 µg of this antibody from a representative lot detected S100A9/MRP14 in 1X10E6 peripheral blood mononuclear cells.
      Biological Information
      ImmunogenRecombinant protein corresponding to human S100A9/MRP14.
      Clone17
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      IsotypeIgG1κ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • S100A9
      • CAGB
      • CFAG
      • MRP14
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~13 kDa observed. Uncharacterized bands may be observed in some lysates.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human spleen tissue lysate.

      Western Blotting Analysis: 0.5 µg/mL of this antibody detected S100A9/MRP14 in 10 µg of human spleen tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABF276 04055977112115

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies