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MABC699 Anti-PAX3, clone 7D8G7 Antibody

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MABC699
100 µL  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RWB, ELISAMAscitesMonoclonal Antibody
      Description
      Catalogue NumberMABC699
      DescriptionAnti-PAX3, clone 7D8G7 Antibody
      Alternate Names
      • Paired box protein Pax-3
      • HuP2
      Background InformationPaired box protein Pax-3, also known as HuP2, and encoded by the gene name PAX3 or HUP2, is a transcription factor that may be involved in regulating cell proliferation, migration, and apoptosis. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma.
      References
      Product Information
      FormatAscites
      PresentationMouse monoclonal IgG1 ascitic fluid with up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect PAX3 using this Anti-PAX3, clone 7D8G7 Antibody validated for use in western blotting & ELISA.
      Key Applications
      • Western Blotting
      • ELISA
      Application NotesELISA: A representative lot was used on control antigen (100 ng) and Antigen (10 ng, 50 ng, 100 ng) in ELISA (Direct).
      Biological Information
      ImmunogenPurified recombinant fragment of human PAX3 expressed in E. Coli
      Clone7D8G7
      HostMouse
      IsotypeIgG1
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • PAX3
      • HUP2
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight~53 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in A549, A431, Jurkat, rat spleen, and mouse liver lysates.

      Western Blotting Analysis: A 1:500-1:2,000 dilution of this antibody detected PAX3 in A549, A431, Jurkat, rat spleen, and mouse liver lysates.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABC699 04053252955334