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438190 Anti-LRP, Heavy Chain Mouse mAb (8G1)

This Anti-LRP, Heavy Chain Mouse mAb (8G1) is validated for use in ELISA, FC, Immunoblotting, IP, Paraffin Sections, Neutralization Studies for the detection of LRP, Heavy Chain.

Anti-LRP, Heavy Chain Mouse mAb (8G1) MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Anti-Low Density Lipoprotein Receptor-Related Protein

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438190
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Overview

Replacement Information

Key Spec Table

Species ReactivityHostAntibody Type
HMMonoclonal Antibody

Pricing & Availability

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438190-100UGCN
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      		 Glass bottle 100 μg
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      Description
      OverviewRecognizes the ~515 kDa LRP heavy chain protein.
      Catalogue Number438190
      Brand Family Calbiochem®
      SynonymsAnti-Low Density Lipoprotein Receptor-Related Protein
      References
      ReferencesMikhailenko, I., et al. 2001. J. Biol. Chem. 276, 39484.
      Rebeck, W.G., et al. 2001. Mol. Brain Res. 87, 238.
      Strickland, D.K., et al. 1990. J. Biol. Chem. 265, 17401.
      Product Information
      FormLiquid
      FormulationIn 100 mM NaCl, 50 mM phosphate buffer, pH 7.4.
      PreservativeNone
      Quality LevelMQ100
      Applications
      Key Applications Enzyme-Linked Immunosorbent Assay
      Flow Cytometry
      Immunoblotting (Western Blotting)
      Immunoprecipitation
      Neutralization Studies
      Paraffin Sections
      Application NotesELISA (see comments)
      Flow Cytometry (see comments)
      Immunoblotting (1-5 µg/ml)
      Immunoprecipitation (see comments)
      Paraffin Sections (1-10 µg/ml)
      Neutralization Studies (see comments)
      Application CommentsRecognizes the low density heavy chain (~515 kDa) by immunoblotting under non-reducing conditions. This antibody has also been reported to work for immunoprecipitation, flow cytometry, and ELISA. Variables associated with assay conditions will dictate the proper working dilution.
      Biological Information
      Immunogennative LRP from human placenta
      ImmunogenHuman
      Clone8G1
      HostMouse
      IsotypeIgG₁
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Concentration Label Please refer to vial label for lot-specific concentration
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      438190-100UGCN 04055977187007

      Documentation

      Anti-LRP, Heavy Chain Mouse mAb (8G1) SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-LRP, Heavy Chain Mouse mAb (8G1) Certificates of Analysis

      TitleLot Number
      438190

      References

      Reference overview
      Mikhailenko, I., et al. 2001. J. Biol. Chem. 276, 39484.
      Rebeck, W.G., et al. 2001. Mol. Brain Res. 87, 238.
      Strickland, D.K., et al. 1990. J. Biol. Chem. 265, 17401.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision07-August-2007 RFH
      SynonymsAnti-Low Density Lipoprotein Receptor-Related Protein
      ApplicationELISA (see comments)
      Flow Cytometry (see comments)
      Immunoblotting (1-5 µg/ml)
      Immunoprecipitation (see comments)
      Paraffin Sections (1-10 µg/ml)
      Neutralization Studies (see comments)
      DescriptionPurified mouse monoclonal antibody. Recognizes the ~515 kDa LRP heavy chain protein.
      BackgroundInhibits the binding of LRP (Low Density Lipoprotein Receptor-Related Protein) to α2-macroglobulin. LRP contributes to the pathology of Alzheimer's disease by influencing both the production and clearance of the β-amyloid peptide.
      HostMouse
      Immunogen speciesHuman
      Immunogennative LRP from human placenta
      Clone8G1
      IsotypeIgG₁
      Specieshuman
      FormLiquid
      FormulationIn 100 mM NaCl, 50 mM phosphate buffer, pH 7.4.
      Concentration Label Please refer to vial label for lot-specific concentration
      PreservativeNone
      CommentsRecognizes the low density heavy chain (~515 kDa) by immunoblotting under non-reducing conditions. This antibody has also been reported to work for immunoprecipitation, flow cytometry, and ELISA. Variables associated with assay conditions will dictate the proper working dilution.
      Storage Avoid freeze/thaw
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Standard Handling
      ReferencesMikhailenko, I., et al. 2001. J. Biol. Chem. 276, 39484.
      Rebeck, W.G., et al. 2001. Mol. Brain Res. 87, 238.
      Strickland, D.K., et al. 1990. J. Biol. Chem. 265, 17401.