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454202 8-Methoxymethyl-3-isobutyl-1-methylxanthine - CAS 78033-08-6 - Calbiochem

Overview

Key Spec Table

CAS #Empirical Formula
78033-08-6C₁₂H₁₈N₄O₃

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454202-10MGCN
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      Description
      OverviewA cell-permeable selective inhibitor of Ca2+-calmodulin-dependent phosphodiesterase (PDE I; IC50 = 4 µM).
      Catalogue Number454202
      Brand Family Calbiochem®
      Synonyms8-Methoxymethyl-IBMX
      References
      ReferencesJackson, E.K., et al. 1997. J. Cardiovasc. Pharmacol. 30, 798.
      Ahn, H.S., et al. 1989. Biochem. Pharmacol. 38, 3331.
      Han, P., et al. 1989. J. Biol. Chem. 274, 22337.
      Product Information
      CAS number78033-08-6
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₁₂H₁₈N₄O₃
      Chemical formulaC₁₂H₁₈N₄O₃
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Primary TargetPDE 1
      Primary Target IC<sub>50</sub>4 µM against Ca2+-calmodulin-dependent phosphodiesterase (PDE I)
      Purity≥98% by TLC
      Physicochemical Information
      Cell permeableY
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +15°C to +30°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
      Global Trade Item Number
      Catalogue Number GTIN
      454202-10MGCN 04055977204742