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575001 α-Synuclein, Human, Recombinant, E. coli

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: NACP

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575001
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Overview

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575001-200UGCN
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      		 Plastic ampoule 200 μg
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      Description
      OverviewRecombinant, human α-synuclein expressed in E. coli. α-Synuclein is an acidic neuronal protein of 140 amino acids (amino acid residues 1 -140). This enzyme has been implicated in the pathogenesis of Parkinson’s disease and related neurodegenerative disorders, and more recently, to be an important regulatory component of vesicular transport in neuronal cells.
      Catalogue Number575001
      Brand Family Calbiochem®
      SynonymsNACP
      References
      ReferencesKahle, P.J, et al. 2001. Am. J. Pathol. 159, 2215.
      Kim, J. 1997. Mol. Cells 7, 78.
      Paik, S.R. 1997. Arch. Biochem. Biophys. 344, 325.
      Jakes, R., et al. 1994. FEBS Lett. 345, 27.
      Ueda, K., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 11282.
      Product Information
      FormLiquid
      FormulationIn 100 mM NaCl, 20 mM Tris-HCl, 1 mM MgCl₂, pH 7.5.
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥95% by SDS-PAGE
      Concentration Label Please refer to vial label for lot-specific concentration
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      575001-200UGCN 04055977189193

      Documentation

      α-Synuclein, Human, Recombinant, E. coli SDS

      Title

      Safety Data Sheet (SDS) 

      α-Synuclein, Human, Recombinant, E. coli Certificates of Analysis

      TitleLot Number
      575001

      References

      Reference overview
      Kahle, P.J, et al. 2001. Am. J. Pathol. 159, 2215.
      Kim, J. 1997. Mol. Cells 7, 78.
      Paik, S.R. 1997. Arch. Biochem. Biophys. 344, 325.
      Jakes, R., et al. 1994. FEBS Lett. 345, 27.
      Ueda, K., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 11282.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision12-September-2008 RFH
      SynonymsNACP
      DescriptionRecombinant, human α-synuclein expressed in E. coli. An acidic neuronal protein consisting of 140 amino acids that has been implicated in the pathogenesis of Parkinson's disease and related neurodegenerative disorders. Also reported to be an important regulatory component of vesicular transport in neuronal cells. The apparent molecular weight by SDS-PAGE is ~19-20 kDa.
      FormLiquid
      FormulationIn 100 mM NaCl, 20 mM Tris-HCl, 1 mM MgCl₂, pH 7.5.
      Concentration Label Please refer to vial label for lot-specific concentration
      Purity≥95% by SDS-PAGE
      Storage Avoid freeze/thaw
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Standard Handling
      ReferencesKahle, P.J, et al. 2001. Am. J. Pathol. 159, 2215.
      Kim, J. 1997. Mol. Cells 7, 78.
      Paik, S.R. 1997. Arch. Biochem. Biophys. 344, 325.
      Jakes, R., et al. 1994. FEBS Lett. 345, 27.
      Ueda, K., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 11282.