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681525 Wiskostatin - CAS 253449-04-6 - Calbiochem

A cell-permeable N-alkylated carbazole derivative that selectively blocks actin filament assembly.

Wiskostatin - CAS 253449-04-6 - Calbiochem: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。
Primary Target: N-WASP (neural Wiskott Aldrich syndrome protein)
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681525
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概要

主要スペック表

CAS #Empirical Formula
253449-04-6C₁₇H₁₈Br₂N₂O

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カタログ番号 在庫状況包装 Qty/Pk 価格 数量
681525-1MGCN
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      		 樹脂ｱﾝﾌﾟﾙ 1 mg
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      681525-5MGCN
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          		 樹脂ｱﾝﾌﾟﾙ 5 mg
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          Description
          OverviewA cell-permeable N-alkylated carbazole derivative that selectively blocks actin filament assembly. Acts as a selective, reversible inhibitor of N-WASP (neural Wiskott Aldrich syndrome protein), a signal integrating protein. Appears to bind to N-WASP, stabilize the autoinhibited conformation and prevent the activation of Arp2/3 (actin-related protein 2/3) complex.
          Catalogue Number681525
          Brand Family Calbiochem®
          References
          ReferencesPeterson, J.R., et al. 2004. Nat. Struct. Mol. Biol. 11, 747.
          Peterson, J.R., and Mitchison, T.J. 2002. Chem. Biol. 9, 1275.
          Product Information
          CAS number253449-04-6
          ATP CompetitiveN
          FormWhite solid
          Hill FormulaC₁₇H₁₈Br₂N₂O
          Chemical formulaC₁₇H₁₈Br₂N₂O
          ReversibleY
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Biological Information
          Primary TargetN-WASP (neural Wiskott Aldrich syndrome protein)
          Purity≥95% by HPLC
          Physicochemical Information
          Cell permeableY
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Global Trade Item Number
          カタログ番号 GTIN
          681525-1MGCN 04055977260090
          681525-5MGCN 04055977260106