Millipore Sigma Vibrant Logo

GF174 Sonic HedgeHog (Shh) Protein, Human Recombinant

The hedgehog (hh) gene encoding a secreted protein was originally identified in Drosophila as a segment polarity gene.

Sonic HedgeHog (Shh) Protein, Human Recombinant: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。
UniProt Number: Q15465
View This Product on Sigma-Aldrich
GF174
25 µg  
価格を検索中…
価格が見つかりません
Minimum Quantity needs to be mulitiple of
Maximum Quantity is
弊社照会 詳細を表示　
値引
()
 
—
弊社照会
—
現在国内在庫なし 現在国内在庫なし
現在国内在庫有り 
販売中止
在庫僅少
現在国内在庫あり
    Remaining : Will advise
      Remaining : Will advise
      注文対象外
      お問合せください
      Contact Customer Service

       

      お問合せください

      概要

      Replacement Information

      主要スペック表

      SourcePurity
      E. coli.Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
      Description
      Catalogue NumberGF174
      DescriptionSonic HedgeHog (Shh) Protein, Human Recombinant
      Alternate Names
      • SHH
      • HHG-1
      Background InformationThe hedgehog (hh) gene encoding a secreted protein was originally identified in Drosophila as a segment polarity gene. The vertebrate homologues of hh comprise several proteins including sonic hedgehog (Shh), Indian hedgehog (Ihh), and Desert hedgehog (Dhh). Hedgehog proteins are important signaling molecules during embryonic development. Shh is expressed in key embryonic tissues such as the Hensen’s node, the zone of polarizing activity in the posterior limb bud, the notochord, and the floor plate of the neural tube. Shh is involved in regulating the patterning of the developing central nervous system, somite, and limb. Shh plays an important role in the development of particular tissues such as whisker, hair, foregut, tooth and bone. Evidence also suggests that Shh is involved in regulating stem cell fates of neural and hematopoietic lineages, and that aberrant Shh signaling is implicated in basal cell carcinomas and other diseases. Shh genes are highly conserved and have been identified in a variety of species including human, mouse, frog, fish, and chicken. Recombinant E. coli derived Human Sonic HedgeHog is a 20.0 kDa protein consisting of 176 amino acid residues, including an N-terminal Ile-Val-Ile sequence substituted for the natural occurring chemically modified Cys residue.
      References
      Product Information
      PresentationProduct is filtered through a 0.2 micron filter before lyophilization.
      Quality LevelMQ100
      Applications
      ApplicationThe hedgehog (hh) gene encoding a secreted protein was originally identified in Drosophila as a segment polarity gene.
      Biological Information
      PurityProduct is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
      SourceE. coli.
      Cross ReactivityNone
      UniProt Number
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceBioactivity assay: Determined by its ability to induce alkaline phosphatase production by C3H/10T1/2 (CCL-226) cells. The expected ED50 for this effect is 0.8-1.0 μg/ml.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore at -20°C for up to 6 months from date of receipt.
      Packaging Information
      Material Size25 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      カタログ番号 GTIN
      GF174 04053252691393

      Documentation

      Sonic HedgeHog (Shh) Protein, Human Recombinant (M)SDS

      タイトル

      英語版製品安全データシート（(M)SDS） 

      Sonic HedgeHog (Shh) Protein, Human Recombinant 試験成績書（CoA）

      タイトルロット番号
      Recombinant Human -2789582 2789582
      Recombinant Human Sonic HedgeHog (Shh) - 2373512 2373512
      Recombinant Human Sonic HedgeHog (Shh) - 2382207 2382207
      Recombinant Human Sonic HedgeHog (Shh) - 2388364 2388364
      Recombinant Human -2634658 2634658
      Recombinant Human -2659614 2659614
      Recombinant Human -2669996 2669996
      Recombinant Human -2691470 2691470
      Recombinant Human -2700271 2700271
      Recombinant Human -2726078 2726078
      Show more

      カタログ

      タイトル
      New Products: Volume 3, 2012

      関連製品＆アプリケーション

      製品ファミリー

      サイトカインおよび成長因子

      メルクミリポアは、細胞培養、幹細胞分化誘導あるいはELISA実験用に、高純度かつ高活性のヒト、マウスおよびラットのサイトカインや成長因子を幅広く提供しています。
      詳細はこちら >>

      カテゴリー

      Life Science Research > タンパク質と酵素 > Cytokines & Growth Factors
      Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Cytokines & Growth Factors