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505986 SR95531 (Gabazine) - CAS 104104-50-9 - Calbiochem

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505986
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概要

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CAS #Empirical Formula
104104-50-9C₁₅H₁₇N₃O₃•HBr

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5.05986.0001
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      ガラスビン 10 mg
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      Description
      OverviewA selective, competitive antagonist of GABAA receptor (IC50 = 440 nM) that does not affect pentobarbitone or etomidate- induced currents even at high concentrations (~100 µM). Also shown to block glycine receptors, but with low affinity (Kb = 190 µM).
      Catalogue Number505986
      Brand Family Calbiochem®
      SynonymsGABAA Receptor Antagonist, SR-95531, Gabazine, SR95531, SR 95531
      References
      ReferencesMuroi, Y., et al. 2009. Biophys. J. 96, 499.
      Beato, M., et al. 2007. J. Physiol. 580, 171.
      Uchida, I., et al. 1996. Eur. J. Pharmacol. 307, 89.
      Product Information
      CAS number104104-50-9
      FormWhite solid
      Hill FormulaC₁₅H₁₇N₃O₃•HBr
      Chemical formulaC₁₅H₁₇N₃O₃•HBr
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetGABAA
      Primary Target IC<sub>50</sub>440 nM
      Purity≥98% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      カタログ番号 GTIN
      5.05986.0001 04055977262582

      Documentation

      SR95531 (Gabazine) - CAS 104104-50-9 - Calbiochem (M)SDS

      タイトル

      英語版製品安全データシート((M)SDS) 

      参考資料

      参考資料の概要
      Muroi, Y., et al. 2009. Biophys. J. 96, 499.
      Beato, M., et al. 2007. J. Physiol. 580, 171.
      Uchida, I., et al. 1996. Eur. J. Pharmacol. 307, 89.
      データシート

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision20-September-2013 JSW
      SynonymsGABAA Receptor Antagonist, SR-95531, Gabazine, SR95531, SR 95531
      DescriptionA selective, competitive antagonist of GABAA receptor (IC50 = 440 nM) that does not affect pentobarbitone or etomidate- induced currents even at high concentrations (~100 mM). Also shown to block glycine receptors, but with low affinity (Kb = 190 mM).
      FormWhite solid
      CAS number104104-50-9
      Chemical formulaC₁₅H₁₇N₃O₃•HBr
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityH₂O (25 mM)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesMuroi, Y., et al. 2009. Biophys. J. 96, 499.
      Beato, M., et al. 2007. J. Physiol. 580, 171.
      Uchida, I., et al. 1996. Eur. J. Pharmacol. 307, 89.