数量	カタログ番号	注文内容	Qty/Pk	価格
			96-Well Plate

数量	カタログ番号	注文内容	Qty/Pk	価格
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

554325 Sigma-AldrichResveratrol - CAS 501-36-0 - Calbiochem

A phenolic product found in both grape skins and wines.

Resveratrol - CAS 501-36-0 - Calbiochem: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。

(M)SDS
試験成績書（CoA）
参考資料
Data Sheet

同義語: trans-3,4ʹ,5-Trihydroxystilbene

Primary Target: COX-1

View This Product on Sigma-Aldrich

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概要

Replacement Information

主要スペック表

CAS #	Empirical Formula
501-36-0	C₁₄H₁₂O₃

価格＆在庫状況

カタログ番号	在庫状況	包装	Qty/Pk	価格	数量
554325-25MGCN	在庫状況検索中… — 現在国内在庫なし現在国内在庫有り販売中止在庫僅少現在国内在庫あり在庫を照会するにはログインしてください現在国内在庫有り現在国内在庫なし現在国内在庫有り Remaining : Will advise Remaining : Will advise 注文対象外お問合せください Contact Customer Service お問合せくださいお問合せください	樹脂ｱﾝﾌﾟﾙ	25 mg	価格を検索中… 価格が見つかりません Minimum Quantity needs to be mulitiple of Maximum Quantity is 弊社照会詳細を表示　値引 () — 弊社照会納入価格を閲覧するにはログインしてください	在庫状況を照会 —	お気に入り/ショッピングリストに追加お気に入り/ショッピングリストに追加お気に入りに追加されました

Description
Overview	A phenolic product found in both grape skins and wines. Has antifungal, antitumor, and antioxidative properties. A specific inhibitor of cyclooxygenase-1 (COX-1; ED₅₀ = 15 µM). Also inhibits the hydroxyperoxidase activity of COX-1 (ED₅₀ = 3.7 µM). Strongly inhibits insoluble transthyretin (TTR) amyloid fibril formation. Inhibits phorbol ester-induced free radical formation in HL-60 cells (ED₅₀ = 27 µM) and acts as an anti-mutagenic agent (ED₅₀ = 15 µM) in TM677 cells treated with DMBA. Also a selective inhibitor of P450 1A1. Reported to activate sirtuins and promote the survival of eukaryotic cells.
Catalogue Number	554325
Brand Family	Calbiochem®
Synonyms	trans-3,4ʹ,5-Trihydroxystilbene

References
References	Howitz, K.T., et al. 2003. Nature 425, 191. Lin, H.Y., et al. 2002. J. Urol. 168, 748. Klabunde, T., et al. 2000. Nat. Struct. Biol. 7, 312. Chun, Y.J., et al. 1999. Biochem. Biophys. Res. Commun. 262, 20. Jang, M., et al. 1997. Science 275, 218. Chen, C.K., et al. 1996. Gen. Pharmacol. 27, 363.

Product Information
CAS number	501-36-0
ATP Competitive	N
Form	Off-white solid
Hill Formula	C₁₄H₁₂O₃
Chemical formula	C₁₄H₁₂O₃
Reversible	N
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Primary Target	COX-1
Primary Target IC<sub>50</sub>	ED50 = 15 µM against COX-1
Purity	≥98% by HPLC

Physicochemical Information
Cell permeable	N

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	+2°C to +8°C
Protect from Light	Protect from light
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
カタログ番号	GTIN
554325-25MGCN	04055977193053

Documentation

Resveratrol - CAS 501-36-0 - Calbiochem (M)SDS

タイトル
英語版製品安全データシート（(M)SDS）

Resveratrol - CAS 501-36-0 - Calbiochem 試験成績書（CoA）

タイトル	ロット番号
554325	ロット番号を入力

参考資料

参考資料の概要
Howitz, K.T., et al. 2003. Nature 425, 191. Lin, H.Y., et al. 2002. J. Urol. 168, 748. Klabunde, T., et al. 2000. Nat. Struct. Biol. 7, 312. Chun, Y.J., et al. 1999. Biochem. Biophys. Res. Commun. 262, 20. Jang, M., et al. 1997. Science 275, 218. Chen, C.K., et al. 1996. Gen. Pharmacol. 27, 363.

データシート

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	17-December-2018 JSW
Synonyms	trans-3,4ʹ,5-Trihydroxystilbene
Description	A phenolic product found in both grape skin and wines. Has anti-fungal, anti-tumor and antioxidative properties. A specific inhibitor of cyclooxygenase-1 (COX-1; ED₅₀ = 15 µM). Also inhibits the hydroxyperoxidase activity of COX-1 (ED₅₀ = 3.7 µM). Inhibits phorbol ester-induced free radical formation in HL-60 cells (ED₅₀ = 27 µM) and acts as an anti-mutagenic agent (ED₅₀ = 15 µM) in TM677 cells treated with DMBA. Also selectively inhibits P450 1A1. Reported to activate sirtuins and promote the survival of eukaryotic cells.
Form	Off-white solid
CAS number	501-36-0
Chemical formula	C₁₄H₁₂O₃
Structure formula
Purity	≥98% by HPLC
Solubility	DMSO (50 mg/ml)
Storage	Protect from light +2°C to +8°C
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity	Standard Handling
Merck USA index	14, 8158
References	Howitz, K.T., et al. 2003. Nature 425, 191. Lin, H.Y., et al. 2002. J. Urol. 168, 748. Klabunde, T., et al. 2000. Nat. Struct. Biol. 7, 312. Chun, Y.J., et al. 1999. Biochem. Biophys. Res. Commun. 262, 20. Jang, M., et al. 1997. Science 275, 218. Chen, C.K., et al. 1996. Gen. Pharmacol. 27, 363.

カテゴリー

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Neurobiology / Neurodegeneration > Amyloidogenesis Inhibitors

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Lipid Signaling Inhibitors > Cyclooxygenase (COX) Inhibitors

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