Millipore Sigma Vibrant Logo

HTS029RTA Ready-to-Assay™ Human Recombinant H3 Histamine Receptor Frozen Cells

Human H3 GPCR frozen cells for Calcium Flux FLIPR Assays.

Host Cell: Chem-3 Entrez Gene Number: NM_002107.3
HTS029RTA
1 kit  
価格を検索中…
価格が見つかりません
Minimum Quantity needs to be mulitiple of
Maximum Quantity is
弊社照会 詳細を表示　
値引
()
 
—
弊社照会
—
現在国内在庫なし 現在国内在庫なし
現在国内在庫有り 
販売中止
在庫僅少
現在国内在庫あり
    Remaining : Will advise
      Remaining : Will advise
      注文対象外
      お問合せください
      Contact Customer Service

       

      お問合せください

      概要

      Replacement Information

      主要スペック表

      SpeciesHost CellsProtein Target
      Human Chem-3H3
      Description
      Catalogue NumberHTS029RTA
      Trade Name
      • Ready-to-Assay
      DescriptionReady-to-Assay™ Human Recombinant H3 Histamine Receptor Frozen Cells
      Background InformationMillipore’s Ready-to-Assay GPCR frozen cells are designed for simple, rapid calcium assays with no requirement for intensive cell culturing. Millipore has optimized the freezing conditions to provide cells with high viability and functionality post-thaw. The user simply thaws the cells, resuspends them in media, and allows them to recover for 24 hours. The following day the cells are counted, plated, and assayed for calcium response.

      The histamine H3 receptor was defined pharmacologically to be a presynaptic histamine receptor that binds selectively to R-(α)-methylhistamine and inhibits neurotransmitter release in the central and peripheral nervous systems (Hill et al., 1997). Molecular cloning of the H3 receptor confirmed it to be a Gi-coupled receptor widely expressed at high levels in the brain (Lovenberg et al., 1999). H3 presents a potential therapeutic target for disorders of the central nervous system involving attention, cognition and feeding (Leurs et al., 2005). Millipore’s cloned human H3-expressing cell line is made in the Chem-3 host, which supports high levels of recombinant H3 expression on the cell surface for functional detection via the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for agonists, antagonists and modulators at H3.
      References
      Product Information
      Components
      • Pack contains 2 vials of mycoplasma-free cells, 1 ml per vial. Fifty (50) mL of Media Component.
      Quality LevelMQ100
      Applications
      ApplicationHuman H3 GPCR frozen cells for Calcium Flux FLIPR Assays.
      Key Applications
      • Calcium Flux Assays
      Biological Information
      Entrez Gene Number
      GPCR ClassA
      Host CellsChem-3
      Protein TargetH3
      Target Sub-FamilyHistamine
      Cell Line Type
      • GPCR Cell Lines
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • This product contains genetically modified organisms (GMO). Within the EU GMOs are regulated by Directives 2001/18/EC and 2009/41/EC of the European Parliament and of the Council and their national implementation in the member States respectively. This legislation obliges Merck to request certain information about you and the establishment where the GMOs are being handled. Click here for Enduser Declaration (EUD) Form.
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Packaging Information
      Material Size1 kit
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      カタログ番号 GTIN
      HTS029RTA 04053252820618

      Documentation

      関連製品＆アプリケーション

      製品ファミリー

      ChemiSCREEN™ GPCR Stable Cell Lines, Membranes Preparation and Ready-to-Assay™ Frozen Cells

      Millipore offers a large selection of robust and reliable G-protein coupled receptor products, including Stable Cell Lines, Membrane Preparations, and Frozen Cells. See below for GPCR research tools.
      詳細はこちら >>

      関連製品: Brand Facete

      Ready-to-Assay™

      カテゴリー

      Life Science Research > Cell Culture and Systems > Cell Lines > GPCR Frozen Cells
      Life Science Research > Drug Discovery and Development > GPCR Cell Lines & Assays > GPCR Frozen Cells