Millipore Sigma Vibrant Logo

553008 Raf1 Kinase Inhibitor I - CAS 220904-83-6 - Calbiochem

The Raf1 Kinase Inhibitor I, also referenced under CAS 220904-83-6, controls the biological activity of Raf1 Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephospho

 More>>
Raf1 Kinase Inhibitor I - CAS 220904-83-6 - Calbiochem: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。

同義語: 5-Iodo-3-[(3,5-dibromo-4-hydroxyphenyl)methylene]-2-indolinone, GW 5074

Primary Target: CRAFI kinase
View This Product on Sigma-Aldrich
553008
価格＆在庫状況を照会

概要

主要スペック表

CAS #Empirical Formula
220904-83-6C₁₅H₈Br₂INO₂

価格＆在庫状況

カタログ番号 在庫状況包装 Qty/Pk 価格 数量
553008-1MGCN
—
現在国内在庫なし 現在国内在庫なし
現在国内在庫有り 
販売中止
在庫僅少
現在国内在庫あり
    Remaining : Will advise
      Remaining : Will advise
      注文対象外
      お問合せください
      Contact Customer Service

      		 樹脂ｱﾝﾌﾟﾙ 1 mg
      価格が見つかりません
      Minimum Quantity needs to be mulitiple of
      Maximum Quantity is
      弊社照会 詳細を表示　
      値引
      ()
       
      —
      弊社照会
      		 —
      お気に入り/ショッピングリストに追加
      Description
      OverviewA potent, cell-permeable, reversible, and ATP-competitive cRAF1 kinase inhibitor (IC50 = 9 nM). Shows ≥100-fold selectivity for Raf kinase versus Cdk1, Cdk2, c-Src, ERK2, MEK, p38, Tie2, VEGFR2, and c-Fms. Predicted broad spectrum antitumor agents. A 10 mM (500 µg/96 µl) solution of Raf1 Inhibitor I (Cat. No. 553003) in DMSO is also available.
      Catalogue Number553008
      Brand Family Calbiochem®
      Synonyms5-Iodo-3-[(3,5-dibromo-4-hydroxyphenyl)methylene]-2-indolinone, GW 5074
      References
      ReferencesLackey, K., et al. 2000. Bioorg. Med. Chem. Lett. 10, 223.
      Product Information
      CAS number220904-83-6
      ATP CompetitiveY
      FormDark orange solid
      Hill FormulaC₁₅H₈Br₂INO₂
      Chemical formulaC₁₅H₈Br₂INO₂
      ReversibleY
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Primary TargetCRAFI kinase
      Primary Target IC<sub>50</sub>9 nM
      Purity≥97% by HPLC
      Physicochemical Information
      Cell permeableY
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.



      From Catalog:
      Desc. Field- added "Predicted broad spectrum antitumor agents.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Global Trade Item Number
      カタログ番号 GTIN
      553008-1MGCN 04055977193404