Millipore Sigma Vibrant Logo

554718 REV-ERBα Antagonist, SR8278 - CAS 101910-24-1 - Calbiochem

View This Product on Sigma-Aldrich
554718
価格&在庫状況を照会

概要

主要スペック表

CAS #Empirical Formula
101910-24-1C₁₈H₁₉NO₃S₂

価格&在庫状況

カタログ番号 在庫状況包装 Qty/Pk 価格 数量
554718-5MGCN
現在国内在庫なし
現在国内在庫なし
現在国内在庫有り 
販売中止
在庫僅少
現在国内在庫あり
    Remaining : Will advise
      Remaining : Will advise
      注文対象外
      お問合せください
      Contact Customer Service

      ガラスビン 5 mg
      価格が見つかりません
      Minimum Quantity needs to be mulitiple of
      Maximum Quantity is
      弊社照会 詳細を表示 
      値引
      ()
       
      弊社照会
      Description
      OverviewA cell-permeable REV-ERB antagonist that inhibits REV-ERBα transcriptional repression activity (EC50 = 0.47 µM) in a REV-ERB target gene assay. It is also shown to block the ability of GSK4112 to enhance REV-ERB-&alpha-dependent repression (EC50 = 0.35 µM) in a co-transfection assay. Treatment of HepG2 cells with SR8278 at 10 µM results in a significant increase in the expression of either G6Pase and PEPCK mRNA expression, consistent with its antagonistic role against endogenous heme.
      Catalogue Number554718
      Brand Family Calbiochem®
      SynonymsSR8278 SR 8278
      References
      ReferencesKojetin, D., et al. 2010, Chem Bio in press
      Product Information
      CAS number101910-24-1
      FormWhite to yellow-brown solid or gum
      Hill FormulaC₁₈H₁₉NO₃S₂
      Chemical formulaC₁₈H₁₉NO₃S₂
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Purity>95% by HPLC
      Storage and Shipping Information
      Ship Code Shipped with Blue Ice or with Dry Ice
      Toxicity Regulatory Review
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Global Trade Item Number
      カタログ番号 GTIN
      554718-5MGCN 04055977193114