539160 Sigma-AldrichProteasome Inhibitor I - Calbiochem
The Proteasome Inhibitor I controls the biological activity of Proteasome. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
More>> The Proteasome Inhibitor I controls the biological activity of Proteasome. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Less<<Proteasome Inhibitor I - Calbiochem: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。
同義語: PSI
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概要
| Replacement Information |
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主要スペック表
| Empirical Formula |
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| C₃₂H₅₀N₄O₈ |
価格＆在庫状況
| カタログ番号 | 在庫状況 | 包装 | Qty/Pk | 価格 | 数量 | |
|---|---|---|---|---|---|---|
| 539160-1MGCN |
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樹脂ｱﾝﾌﾟﾙ | 1 mg |
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— | |
| 539160-5MGCN |
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樹脂ｱﾝﾌﾟﾙ | 5 mg |
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— |
| Description | |
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| Overview | A cell-permeable, reversible inhibitor of the chymotrypsin-like activity of the multicatalytic proteinase complex (MCP; 20S proteasome) in HT4 cells. Causes the accumulation of ubiquitinated proteins in neuronal cells. Prevents the activation of NF-κB in response to TNF-α and Okadaic Acid (Cat. No. 495604) through inhibition of IκB-α degradation. A 50 mM (5 mg/162 µl) solution of Proteasome Inhibitor I (Cat. No. 539161) in DMSO is also available. |
| Catalogue Number | 539160 |
| Brand Family | Calbiochem® |
| Synonyms | PSI |
| Product Information | |
|---|---|
| ATP Competitive | N |
| Form | White solid |
| Hill Formula | C₃₂H₅₀N₄O₈ |
| Chemical formula | C₃₂H₅₀N₄O₈ |
| Reversible | Y |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
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| Biological Information | |
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| Primary Target | Chymotrypsin-like activity of the multicatalytic proteinase complex (MCP; 20S proteasome) in HT4 cells |
| Purity | ≥90% by HPLC |
| Physicochemical Information | |
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| Cell permeable | Y |
| Peptide Sequence | Z-Ile-Glu(OtBu)-Ala-Leu-CHO |
| Dimensions |
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| Materials Information |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Safety Information |
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| Product Usage Statements |
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| Packaging Information |
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| Transport Information |
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| Supplemental Information |
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| Specifications |
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| Global Trade Item Number | |
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| カタログ番号 | GTIN |
| 539160-1MGCN | 04055977269420 |
| 539160-5MGCN | 04055977269437 |
Documentation
Proteasome Inhibitor I - Calbiochem (M)SDS
| タイトル |
|---|
Proteasome Inhibitor I - Calbiochem 試験成績書（CoA）
| タイトル | ロット番号 |
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| 539160 |
参考資料
| 参考資料の概要 |
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| Griscavage, J.M., et al. 1996. Proc. Natl. Acad. Sci. USA 93, 3308. Mori, S., et al. 1995. J. Biol. Chem. 270, 29447. Figueiredo-Pereira, M.E., et al. 1994. J. Neurochem. 63, 1578. Traenckner, E.B., et al. 1994. EMBO J. 13, 5433. |
カタログ
| タイトル |
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| Caspases and other Apoptosis Related Tools Brochure |
| Proteasomes Technical Bulletin |
引用
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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