数量	カタログ番号	注文内容	Qty/Pk	価格
			96-Well Plate

数量	カタログ番号	注文内容	Qty/Pk	価格
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

527948 Sigma-AldrichPiceatannol - CAS 10083-24-6 - Calbiochem

A cell-permeable, substrate competitive and reversible plant metabolite that inhibits the activity of rat liver protein kinase A catalytic subunit (IC₅₀ = 3 µM), PKC (IC₅₀ = 8 µM), MLCK (IC₅₀ = 12 µM).

Piceatannol - CAS 10083-24-6 - Calbiochem: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。

(M)SDS
試験成績書（CoA）
参考資料
Data Sheet

同義語: trans-3,3ʹ,4,5ʹ-Tetrahydroxystilbene

Primary Target: Activity of rat liver protein kinase A catalytic subunit

View This Product on Sigma-Aldrich

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概要

Replacement Information

主要スペック表

CAS #	Empirical Formula
10083-24-6	C₁₄H₁₂O₄

価格＆在庫状況

カタログ番号	在庫状況	包装	Qty/Pk	価格	数量
527948-1MGCN	在庫状況検索中… — 現在国内在庫なし現在国内在庫有り販売中止在庫僅少現在国内在庫あり在庫を照会するにはログインしてください現在国内在庫有り現在国内在庫なし現在国内在庫有り Remaining : Will advise Remaining : Will advise 注文対象外お問合せください Contact Customer Service お問合せくださいお問合せください	樹脂ｱﾝﾌﾟﾙ	1 mg	価格を検索中… 価格が見つかりません Minimum Quantity needs to be mulitiple of Maximum Quantity is 弊社照会詳細を表示　値引 () — 弊社照会納入価格を閲覧するにはログインしてください	在庫状況を照会 —	お気に入り/ショッピングリストに追加お気に入り/ショッピングリストに追加お気に入りに追加されました

Description
Overview	A cell-permeable, substrate competitive and reversible plant metabolite that inhibits the activity of rat liver protein kinase A catalytic subunit (IC₅₀ = 3 µM), PKC (IC₅₀ = 8 µM), MLCK (IC₅₀ = 12 µM). In RBL-2H3 cells, the selective inhibition of Syk by piceatannol results in inhibition of FceR1-mediated signaling. Also inhibits wheat embryo Ca²⁺-dependent protein kinase (CDPK) (IC₅₀ = 19 µM), and p72^syk (IC₅₀ = 10 µM), a non-receptor tyrosine kinase, relative to Lyn in isolated enzyme preparations. Also possesses anti-leukemic properties. Reported to activate sirtuins and promote the survival of eukaryotic cells.
Catalogue Number	527948
Brand Family	Calbiochem®
Synonyms	trans-3,3ʹ,4,5ʹ-Tetrahydroxystilbene

References
References	Howitz, K.T., et al. 2003. Nature 425, 191. Wang, B.H., et al. 1998. Planta Med. 64, 195. Keely, P.J., and Parise, L.V. 1996. J. Biol. Chem. 271, 26668. Oliver, J.M., et al. 1994. J. Biol. Chem. 269, 29697. Thakkar, K., et al. 1993. J. Med. Chem. 36, 2950. Geahlen, R.L., et al. 1989. Biochem. Biophys. Res. Commun. 165, 241.

Product Information
CAS number	10083-24-6
ATP Competitive	Y
Form	Off-white crystalline solid
Hill Formula	C₁₄H₁₂O₄
Chemical formula	C₁₄H₁₂O₄
Reversible	Y
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Primary Target	Activity of rat liver protein kinase A catalytic subunit
Primary Target IC<sub>50</sub>	3 µM, 8 µM, and 12 µM against the activity of rat liver protein kinase A catalytic subunit, PKC, and MLCK, respectively
Purity	≥95% by HPLC

Physicochemical Information
Cell permeable	Y

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	+2°C to +8°C
Protect from Light	Protect from light
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot, flush with an inert gas, and freeze (-20°C). Stock solutions are stable for up to 2 weeks at -20°C.

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
カタログ番号	GTIN
527948-1MGCN	07790788051143

Documentation

Piceatannol - CAS 10083-24-6 - Calbiochem (M)SDS

タイトル
英語版製品安全データシート（(M)SDS）

Piceatannol - CAS 10083-24-6 - Calbiochem 試験成績書（CoA）

タイトル	ロット番号
527948	ロット番号を入力

参考資料

参考資料の概要
Howitz, K.T., et al. 2003. Nature 425, 191. Wang, B.H., et al. 1998. Planta Med. 64, 195. Keely, P.J., and Parise, L.V. 1996. J. Biol. Chem. 271, 26668. Oliver, J.M., et al. 1994. J. Biol. Chem. 269, 29697. Thakkar, K., et al. 1993. J. Med. Chem. 36, 2950. Geahlen, R.L., et al. 1989. Biochem. Biophys. Res. Commun. 165, 241.

データシート

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	05-March-2010
Synonyms	trans-3,3ʹ,4,5ʹ-Tetrahydroxystilbene
Description	A cell-permeable, substrate competitive, and reversible plant metabolite that inhibits the activity of rat liver protein kinase A catalytic subunit (IC₅₀ = 3 µM), PKC (IC₅₀ = 8 µM), MLCK (IC₅₀ = 12 µM). In RBL-2H3 cells, the selective inhibition of Syk by piceatannol results in inhibition of FceR1-mediated signaling. Also inhibits wheat embryo Ca²⁺-dependent protein kinase (CDPK) (IC₅₀ = 19 µM), and p72^syk (IC₅₀ = 10 µM), a non-receptor tyrosine kinase, relative to Lyn in isolated enzyme preparations. Also possesses anti-leukemic properties. Reported to activate sirtuins and promote the survival of eukaryotic cells.
Form	Off-white crystalline solid
Intert gas (Yes/No)	Packaged under inert gas
CAS number	10083-24-6
Chemical formula	C₁₄H₁₂O₄
Structure formula
Purity	≥95% by HPLC
Solubility	DMSO (10 mg/ml) or Ethanol (10 mg/ml)
Storage	Protect from light +2°C to +8°C
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot, flush with an inert gas, and freeze (-20°C). Stock solutions are stable for up to 2 weeks at -20°C.
Toxicity	Standard Handling
References	Howitz, K.T., et al. 2003. Nature 425, 191. Wang, B.H., et al. 1998. Planta Med. 64, 195. Keely, P.J., and Parise, L.V. 1996. J. Biol. Chem. 271, 26668. Oliver, J.M., et al. 1994. J. Biol. Chem. 269, 29697. Thakkar, K., et al. 1993. J. Med. Chem. 36, 2950. Geahlen, R.L., et al. 1989. Biochem. Biophys. Res. Commun. 165, 241.

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