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52332 Phenylmethylsulfonyl Fluoride - CAS 329-98-6 - Calbiochem

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52332
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概要

Replacement Information

主要スペック表

CAS #Empirical Formula
329-98-6C₇H₇FO₂S

価格&在庫状況

カタログ番号 在庫状況包装 Qty/Pk 価格 数量
52332-1GMCN
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      アルミニウムカン 1 gm
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      52332-25GMCN
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          紙ケース 25 gm
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          52332-5GMCN
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              ガラスビン 5 gm
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              Description
              OverviewIrreversible inhibitor of serine proteases. Its mechanism of action is analogous to that of diisopropylfluorophosphate. PMSF causes sulfonylation of the active-site serine residues. Also reported to inhibit internucleosomal DNA fragmentation in immature thymocytes. For a related, more stable inhibitor, see AEBSF (Cat. No. 101500).
              Catalogue Number52332
              Brand Family Calbiochem®
              SynonymsBenzylsulfonyl Fluoride, PMSF
              References
              ReferencesSeitz, R., et al. 1993. Int. J. Cancer 53, 514.
              Weaver, V.M., et al. 1993. Biochem. Cell. Biol. 71, 488.
              Bourgain, R.H., et al. 1992. Adv. Exp. Med. Biol. 316, 427.
              Chang, C.T., et al. 1992. Biochem. Int. 28, 707.
              Product Information
              CAS number329-98-6
              ATP CompetitiveN
              FormWhite to off-white crystalline solid
              Hill FormulaC₇H₇FO₂S
              Chemical formulaC₇H₇FO₂S
              Reconstitutiont½ = 1 hour at pH 7.5. Effective concentration: 50 μM.
              ReversibleN
              Structure formula ImageStructure formula Image
              Quality LevelMQ200
              Applications
              Biological Information
              Primary Targetserine proteases
              Purity≥99% by GC
              Physicochemical Information
              Cell permeableN
              Dimensions
              Materials Information
              Toxicological Information
              Safety Information according to GHS
              RTECSXT8040000
              Safety Information
              R PhraseR: 34

              Causes burns.
              S PhraseS: 26-36/37/39-45

              In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
              Wear suitable protective clothing, gloves and eye/face protection.
              In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
              Product Usage Statements
              Storage and Shipping Information
              Ship Code Ambient Temperature Only
              Toxicity Corrosive
              Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
              Storage +15°C to +30°C
              Protect from Moisture Protect from moisture
              Do not freeze Ok to freeze
              Special InstructionsFollowing reconstitution, refrigerate (4°C). Stock solutions are stable for up to 9 months at 4°C.
              Packaging Information
              Transport Information
              Supplemental Information
              Specifications
              Global Trade Item Number
              カタログ番号 GTIN
              52332-1GMCN 07790788051044
              52332-25GMCN 04055977271508
              52332-5GMCN 04055977271515

              Documentation

              Phenylmethylsulfonyl Fluoride - CAS 329-98-6 - Calbiochem (M)SDS

              タイトル

              英語版製品安全データシート((M)SDS) 

              Phenylmethylsulfonyl Fluoride - CAS 329-98-6 - Calbiochem 試験成績書(CoA)

              タイトルロット番号
              52332

              参考資料

              参考資料の概要
              Seitz, R., et al. 1993. Int. J. Cancer 53, 514.
              Weaver, V.M., et al. 1993. Biochem. Cell. Biol. 71, 488.
              Bourgain, R.H., et al. 1992. Adv. Exp. Med. Biol. 316, 427.
              Chang, C.T., et al. 1992. Biochem. Int. 28, 707.

              カタログ

              タイトル
              Caspases and other Apoptosis Related Tools Brochure

              引用

              Title
            • Sun, G., et al. 2007. Journal of Bacteriology 189, 6222.
            • データシート

              Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

              Revision19-August-2008 RFH
              SynonymsBenzylsulfonyl Fluoride, PMSF
              DescriptionIrreversible inhibitor of serine proteases. Its mechanism of action is analogous to that of diisopropylfluorophosphate. PMSF causes sulfonylation of the active-site serine residues. Also reported to inhibit internucleosomal DNA fragmentation in immature thymocytes. Effective at a concentration of 50 µM.
              FormWhite to off-white crystalline solid
              CAS number329-98-6
              RTECSXT8040000
              Chemical formulaC₇H₇FO₂S
              Structure formulaStructure formula
              Purity≥99% by GC
              SolubilityEthanol, isopropanol, or methanol
              Storage Protect from moisture
              +15°C to +30°C
              Do Not Freeze Ok to freeze
              Special InstructionsFollowing reconstitution, refrigerate (4°C). Stock solutions are stable for up to 9 months at 4°C.
              Toxicity Corrosive
              ReferencesSeitz, R., et al. 1993. Int. J. Cancer 53, 514.
              Weaver, V.M., et al. 1993. Biochem. Cell. Biol. 71, 488.
              Bourgain, R.H., et al. 1992. Adv. Exp. Med. Biol. 316, 427.
              Chang, C.T., et al. 1992. Biochem. Int. 28, 707.
              Citation
            • Sun, G., et al. 2007. Journal of Bacteriology 189, 6222.