516481 Sigma-AldrichPepstatin A, Synthetic - CAS 26305-03-3 - Calbiochem
Pepstatin A, Synthetic, CAS 26305-03-3, is a reversible inhibitor of aspartic proteases. Inhibits cathepsin D, pepsin, and renin.
More>> Pepstatin A, Synthetic, CAS 26305-03-3, is a reversible inhibitor of aspartic proteases. Inhibits cathepsin D, pepsin, and renin. Less<<同義語: Iva-Val-Val-Sta-Ala-Sta, Isovaleryl-Val-Val-4-amino-3-hydroxy-6-methylheptanoyl-Ala-4-amino-3-hydroxy-6-methylheptanoic Acid
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概要
Replacement Information |
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主要スペック表
CAS # | Empirical Formula |
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26305-03-3 | C₃₄H₆₃N₅O₉ |
価格&在庫状況
カタログ番号 | 在庫状況 | 包装 | Qty/Pk | 価格 | 数量 | |
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516481-100MGCN |
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樹脂アンプル | 100 mg |
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516481-25MGCN |
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樹脂アンプル | 25 mg |
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516481-5MGCN |
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樹脂アンプル | 5 mg |
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Description | |
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Overview | A reversible inhibitor of aspartic proteases. Inhibits cathepsin D, pepsin, and renin. Reported to block apoptosis induced by CA-074 (Cat. No. 205530) in PC12 cell lines. Also available as a 25 mM solution in DMSO (Cat. No. 508437). |
Effective concentration: 1.0 µM. | |
Catalogue Number | 516481 |
Brand Family | Calbiochem® |
Synonyms | Iva-Val-Val-Sta-Ala-Sta, Isovaleryl-Val-Val-4-amino-3-hydroxy-6-methylheptanoyl-Ala-4-amino-3-hydroxy-6-methylheptanoic Acid |
Product Information | |
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CAS number | 26305-03-3 |
ATP Competitive | N |
Form | White solid |
Hill Formula | C₃₄H₆₃N₅O₉ |
Chemical formula | C₃₄H₆₃N₅O₉ |
Optical rotation | Optical rotation: -90.0 ± 5° (c = 0.5, MeOH, 20°C). |
Reversible | Y |
Quality Level | MQ100 |
Applications |
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Biological Information | |
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Primary Target | cathepsin D |
Primary Target IC<sub>50</sub> | EC50 = 1.0 µM in blocking apoptosis induced by CA-074 in PC12 cell lines |
Purity | ≥98% by HPLC |
Physicochemical Information | |
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Cell permeable | N |
Dimensions |
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Materials Information |
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Toxicological Information |
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Safety Information according to GHS | |
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RTECS | SC6155000 |
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Product Usage Statements |
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Supplemental Information |
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Specifications |
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Global Trade Item Number | |
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カタログ番号 | GTIN |
516481-100MGCN | 04055977198812 |
516481-25MGCN | 07790788055837 |
516481-5MGCN | 04055977198836 |
Documentation
Pepstatin A, Synthetic - CAS 26305-03-3 - Calbiochem (M)SDS
タイトル |
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Pepstatin A, Synthetic - CAS 26305-03-3 - Calbiochem 試験成績書(CoA)
タイトル | ロット番号 |
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516481 |
参考資料
参考資料の概要 |
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Isahara, K., et al. 1999. Neuroscience 91, 233. Kanamori, S., et al. 1998. Biochem. Biophys. Res. Commun. 251, 204. Szewczuk, Z., et al. 1992. Int. J. Pept. Prot. Res. 40, 233. Carraway, R.E., et al. 1991. Peptides 12, 107. Eid, M., et al. 1981. Biochem. J. 197, 465. Umezawa, H., et al. 1970. J. Antibiot. 23, 259. |
カタログ
タイトル |
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Western Blotting Tools |
技術情報
タイトル |
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Protein Blotting Handbook: 6th Edition |