Millipore Sigma Vibrant Logo

516481 Pepstatin A, Synthetic - CAS 26305-03-3 - Calbiochem

View This Product on Sigma-Aldrich
516481
価格&在庫状況を照会

概要

Replacement Information

主要スペック表

CAS #Empirical Formula
26305-03-3C₃₄H₆₃N₅O₉

価格&在庫状況

カタログ番号 在庫状況包装 Qty/Pk 価格 数量
516481-100MGCN
在庫状況検索中…
現在国内在庫なし
現在国内在庫なし
現在国内在庫有り 
販売中止
在庫僅少
現在国内在庫あり
    Remaining : Will advise
      Remaining : Will advise
      注文対象外
      お問合せください
      Contact Customer Service

      樹脂アンプル 100 mg
      価格を検索中…
      価格が見つかりません
      Minimum Quantity needs to be mulitiple of
      Maximum Quantity is
      弊社照会 詳細を表示 
      値引
      ()
       
      弊社照会
      516481-25MGCN
      在庫状況検索中…
      現在国内在庫なし
現在国内在庫なし
      現在国内在庫有り 
      販売中止
      在庫僅少
      現在国内在庫あり
        Remaining : Will advise
          Remaining : Will advise
          注文対象外
          お問合せください
          Contact Customer Service

          樹脂アンプル 25 mg
          価格を検索中…
          価格が見つかりません
          Minimum Quantity needs to be mulitiple of
          Maximum Quantity is
          弊社照会 詳細を表示 
          値引
          ()
           
          弊社照会
          516481-5MGCN
          在庫状況検索中…
          現在国内在庫なし
現在国内在庫なし
          現在国内在庫有り 
          販売中止
          在庫僅少
          現在国内在庫あり
            Remaining : Will advise
              Remaining : Will advise
              注文対象外
              お問合せください
              Contact Customer Service

              樹脂アンプル 5 mg
              価格を検索中…
              価格が見つかりません
              Minimum Quantity needs to be mulitiple of
              Maximum Quantity is
              弊社照会 詳細を表示 
              値引
              ()
               
              弊社照会
              Description
              OverviewA reversible inhibitor of aspartic proteases. Inhibits cathepsin D, pepsin, and renin. Reported to block apoptosis induced by CA-074 (Cat. No. 205530) in PC12 cell lines. Also available as a 25 mM solution in DMSO (Cat. No. 508437).
              Effective concentration: 1.0 µM.
              Catalogue Number516481
              Brand Family Calbiochem®
              SynonymsIva-Val-Val-Sta-Ala-Sta, Isovaleryl-Val-Val-4-amino-3-hydroxy-6-methylheptanoyl-Ala-4-amino-3-hydroxy-6-methylheptanoic Acid
              References
              ReferencesIsahara, K., et al. 1999. Neuroscience 91, 233.
              Kanamori, S., et al. 1998. Biochem. Biophys. Res. Commun. 251, 204.
              Szewczuk, Z., et al. 1992. Int. J. Pept. Prot. Res. 40, 233.
              Carraway, R.E., et al. 1991. Peptides 12, 107.
              Eid, M., et al. 1981. Biochem. J. 197, 465.
              Umezawa, H., et al. 1970. J. Antibiot. 23, 259.
              Product Information
              CAS number26305-03-3
              ATP CompetitiveN
              FormWhite solid
              Hill FormulaC₃₄H₆₃N₅O₉
              Chemical formulaC₃₄H₆₃N₅O₉
              Optical rotationOptical rotation: -90.0 ± 5° (c = 0.5, MeOH, 20°C).
              ReversibleY
              Quality LevelMQ100
              Applications
              Biological Information
              Primary Targetcathepsin D
              Primary Target IC<sub>50</sub>EC50 = 1.0 µM in blocking apoptosis induced by CA-074 in PC12 cell lines
              Purity≥98% by HPLC
              Physicochemical Information
              Cell permeableN
              Dimensions
              Materials Information
              Toxicological Information
              Safety Information according to GHS
              RTECSSC6155000
              Safety Information
              Product Usage Statements
              Storage and Shipping Information
              Ship Code Ambient Temperature Only
              Toxicity Standard Handling
              Storage +2°C to +8°C
              Do not freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.
              Packaging Information
              Transport Information
              Supplemental Information
              Specifications
              Global Trade Item Number
              カタログ番号 GTIN
              516481-100MGCN 04055977198812
              516481-25MGCN 07790788055837
              516481-5MGCN 04055977198836

              Documentation

              Pepstatin A, Synthetic - CAS 26305-03-3 - Calbiochem (M)SDS

              タイトル

              英語版製品安全データシート((M)SDS) 

              Pepstatin A, Synthetic - CAS 26305-03-3 - Calbiochem 試験成績書(CoA)

              タイトルロット番号
              516481

              参考資料

              参考資料の概要
              Isahara, K., et al. 1999. Neuroscience 91, 233.
              Kanamori, S., et al. 1998. Biochem. Biophys. Res. Commun. 251, 204.
              Szewczuk, Z., et al. 1992. Int. J. Pept. Prot. Res. 40, 233.
              Carraway, R.E., et al. 1991. Peptides 12, 107.
              Eid, M., et al. 1981. Biochem. J. 197, 465.
              Umezawa, H., et al. 1970. J. Antibiot. 23, 259.

              カタログ

              タイトル
              Western Blotting Tools

              技術情報

              タイトル
              Protein Blotting Handbook: 6th Edition
              データシート

              Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

              Revision11-October-2013 JSW
              SynonymsIva-Val-Val-Sta-Ala-Sta, Isovaleryl-Val-Val-4-amino-3-hydroxy-6-methylheptanoyl-Ala-4-amino-3-hydroxy-6-methylheptanoic Acid
              DescriptionA reversible inhibitor of aspartic proteases. Inhibits cathepsin D, pepsin, and renin. Reported to block apoptosis induced by CA-074 (Cat. No. 205530) in PC12 cells. Effective concentration: 1 µM.
              FormWhite solid
              Recommended reaction conditions
              Activity:
              Activity is measured by inhibition of pepsin. 1 U corresponds to the amount of inhibitor that reduces the activity of pepsin by 1 U (1 U of enzyme corresponds to the amount of enzyme that results in the increases the absorbance at 280 nm by 0.001 per min at pH 2.0, 37°C.)
              CAS number26305-03-3
              RTECSSC6155000
              Chemical formulaC₃₄H₆₃N₅O₉
              Purity≥98% by HPLC
              SolubilityDMSO (1 mg/ml) or Methanol (1 mg/ml)
              Storage +2°C to +8°C
              Do Not Freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.
              Toxicity Standard Handling
              Merck USA index14, 7147
              ReferencesIsahara, K., et al. 1999. Neuroscience 91, 233.
              Kanamori, S., et al. 1998. Biochem. Biophys. Res. Commun. 251, 204.
              Szewczuk, Z., et al. 1992. Int. J. Pept. Prot. Res. 40, 233.
              Carraway, R.E., et al. 1991. Peptides 12, 107.
              Eid, M., et al. 1981. Biochem. J. 197, 465.
              Umezawa, H., et al. 1970. J. Antibiot. 23, 259.