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33-038 PI 3-Kinase Class II HTRF Assay

One-plate kit (384 well plate) of reagents for performing PI 3-Kinase (Class II) 4-step HTRF assays. Suitable for the following Kinases: PI3KC2α, PI3KC2β & PI3KC2γ.

PI 3-Kinase Class II HTRF Assay: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。
33-038
384 wells  Kit capacity: 384 wells
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      概要

      Replacement Information
      Description
      Catalogue Number33-038
      Brand Family Upstate
      Trade Name
      • HTRF
      • Upstate
      DescriptionPI 3-Kinase Class II HTRF Assay
      References
      Product Information
      Components
      • Reaction Buffer (4X)
      • DM A Detection Reagent
      • DM C Detection Reagent
      • DM D Detection Reagent
      • Phosphatidylinositol (1mM)
      • Phosphatidylserine (1mM)
      • Stop Reagent C
      Detection methodHTRF
      Quality LevelMQ300
      Applications
      ApplicationOne-plate kit (384 well plate) of reagents for performing PI 3-Kinase (Class II) 4-step HTRF assays. Suitable for the following Kinases: PI3KC2α, PI3KC2β & PI3KC2γ.
      Key Applications
      • Kinase Assay
      Biological Information
      Species Reactivity
      • Human
      • Mouse
      Analytes Available
      • PI 3-Kinase Class II
      Entrez Gene Number
      Entrez Gene SummaryPhosphoinositide 3-kinase-C2 proteins generate phosphatidylinositol 3-phosphate (PtdIns3P) and phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) that act as second messengers. This protein belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is sensitive to low nanomolar levels of the inhibitor wortmanin. The C2 domain of this protein was shown to bind phospholipids but not Ca2+, which suggests that this enzyme may function in a calcium-independent manner.
      Gene Symbol
      • PI3KC2α
      • PI3KC2β
      • PI3KC2γ
      Target Sub-FamilyPI3K/PI4K
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions12 months at -70°C
      Packaging Information
      Material Size384 wells
      Material PackageKit capacity: 384 wells
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      カタログ番号 GTIN
      33-038 04053252374531

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      Alternative Packsize

      カタログ番号 説明  
      33-039 PI 3-Kinase Class II HTRF Assay 価格＆在庫状況を表示

      製品ファミリー

      Kinase & Phosphatase Products

      Millipore offers a large portfolio of Kinases, Phophatases, Substrates, Inhibitors, Kits, reagents & tools for Signaling research. See below for a list of these products, in multiple pack sizes.
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      関連製品: Brand Facete

      HTRF™

      カテゴリー

      Life Science Research > Protein Detection and Quantification > Activity Assays > Kinase Assays
      Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Enzyme Assay Kits and Reagents