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33-041 PI 3-Kinase 3-step HTRF™ Assay

Everything you need to perform the PI3 Kinase 3-step HTRF assays (1920 wells).

PI 3-Kinase 3-step HTRF™ Assay: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。
Key Applications: Kinase Assay
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33-041
1920 wells  Kit capacity: 1920 wells
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      概要

      Replacement Information

      主要スペック表

      Species ReactivityKey ApplicationsAnalytes AvailableDetection Methods
      H, MKAPI 3-Kinase HTRF
      Description
      Catalogue Number33-041
      Brand Family Upstate
      Trade Name
      • HTRF
      • Upstate
      DescriptionPI 3-Kinase 3-step HTRF™ Assay
      References
      Product Information
      Components
      • 4X Reaction Buffer
      • PIP2 (substrate, 1mM stock)
      • DM A Reaction Buffer
      • DM B Reaction Buffer
      • DM C Reaction Buffer
      • BPIP3
      • Stop Reagent
      Detection methodHTRF
      Quality LevelMQ100
      Applications
      ApplicationEverything you need to perform the PI3 Kinase 3-step HTRF assays (1920 wells).
      Key Applications
      • Kinase Assay
      Biological Information
      Species Reactivity
      • Human
      • Mouse
      Analytes Available
      • PI 3-Kinase
      Entrez Gene Number
      Entrez Gene SummaryPhosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers.
      Gene Symbol
      • PIK3CA
      • MGC142163
      • PI3K
      • MGC142161
      • p110-alpha
      Target Sub-FamilyPI3K/PI4K
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P42336 # Phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2 with a preference for PtdIns(4,5)P2.
      SIZE: 1068 amino acids; 124284 Da
      SUBUNIT: Heterodimer of a p110 (catalytic) and a p85 (regulatory) subunit. Binds to IRS1 in nuclear extracts. Interacts with RUFY3 (By similarity).
      DISEASE: SwissProt: P42336 # Defects in PIK3CA are associated with colorectal cancer (CRC) [MIM:114500]. & Defects in PIK3CA are associated with breast cancer [MIM:114480]. & Defects in PIK3CA are associated with epithelial ovarian cancer (EOC) [MIM:604370].
      SIMILARITY: SwissProt: P42336 ## Belongs to the PI3/PI4-kinase family. & Contains 1 C2 domain. & Contains 1 PI3K/PI4K domain.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions12 months at -70°C
      Packaging Information
      Material Size1920 wells
      Material PackageKit capacity: 1920 wells
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      カタログ番号 GTIN
      33-041 04053252854385

      関連製品＆アプリケーション

      Alternative Packsize

      カタログ番号 説明  
      33-040 PI 3-Kinase 3-step HTRF™ Assay 価格＆在庫状況を表示
      33-047 PI 3-Kinase 3-step HTRF™ Assay 価格＆在庫状況を表示

      Alternative Format

      カタログ番号 説明  
      33-017 PI 3-Kinase HTRF™ Assay; 1920 wells 価格＆在庫状況を表示

      製品ファミリー

      Kinase & Phosphatase Products

      Millipore offers a large portfolio of Kinases, Phophatases, Substrates, Inhibitors, Kits, reagents & tools for Signaling research. See below for a list of these products, in multiple pack sizes.
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      関連製品: Brand Facete

      HTRF™

      カテゴリー

      Life Science Research > Protein Detection and Quantification > Activity Assays > Kinase Assays