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491207 Novobiocin, Sodium Salt - CAS 1476-53-5 - Calbiochem

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Novobiocin, Sodium Salt - CAS 1476-53-5 - Calbiochem: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。
Primary Target: retrovirus RNA-dependent DNA polymerases
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491207
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概要

Replacement Information

主要スペック表

CAS #Empirical Formula
1476-53-5C₃₁H₃₅N₂O₁₁ · Na

価格＆在庫状況

カタログ番号 在庫状況包装 Qty/Pk 価格 数量
491207-10GMCN
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      Description
      OverviewDNA gyrase inhibitor used for the production of positively supercoiled plasma DNA. Inhibits retrovirus RNA-dependent DNA polymerases. Also a potent inhibitor of ADP ribosylation eliminates the wild-type pMG110 plasmid from E. coli.
      Catalogue Number491207
      Brand Family Calbiochem®
      References
      ReferencesMarcu, M.G., et al. 2000. J. Natl. Cancer Inst. 92, 242.
      Luhrmann, A., et al. 1998. Antimicrob. Agents Chemotherp. 42, 1911.
      Hooper, D.C., et al. 1984. Antimicrob. Agents Chemother. 25, 586.
      Lockshon, D., and Morris, D.R. 1983. Nucleic Acid. Res. 11, 2999.
      Sumiyoshi, Y., et al. 1983. J. Gen. Virol. 64, 2329.
      Staudenbauer, W.L. 1975. J. Mol. Biol. 96, 201.
      Product Information
      CAS number1476-53-5
      ATP CompetitiveN
      FormWhite to yellow solid
      Hill FormulaC₃₁H₃₅N₂O₁₁ · Na
      Chemical formulaC₃₁H₃₅N₂O₁₁ · Na
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetretrovirus RNA-dependent DNA polymerases
      Purity≥90% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSRD5425000
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, refrigerate (4°C). Stock solutions are stable for 3 months at 4°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      カタログ番号 GTIN
      491207-10GMCN 07790788050818

      Documentation

      Novobiocin, Sodium Salt - CAS 1476-53-5 - Calbiochem (M)SDS

      タイトル

      英語版製品安全データシート（(M)SDS） 

      Novobiocin, Sodium Salt - CAS 1476-53-5 - Calbiochem 試験成績書（CoA）

      タイトルロット番号
      491207

      参考資料

      参考資料の概要
      Marcu, M.G., et al. 2000. J. Natl. Cancer Inst. 92, 242.
      Luhrmann, A., et al. 1998. Antimicrob. Agents Chemotherp. 42, 1911.
      Hooper, D.C., et al. 1984. Antimicrob. Agents Chemother. 25, 586.
      Lockshon, D., and Morris, D.R. 1983. Nucleic Acid. Res. 11, 2999.
      Sumiyoshi, Y., et al. 1983. J. Gen. Virol. 64, 2329.
      Staudenbauer, W.L. 1975. J. Mol. Biol. 96, 201.
      データシート

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision22-May-2018 JSW
      DescriptionA DNA gyrase inhibitor that can be used for the production of positively supercoiled plasma DNA. Targets the nucleotide-binding site of gyrase B. Exhibits antibacterial properties. Inhibits retrovirus RNA-dependent DNA polymerases. Inhibits LPS-induced production of pro-inflammatory cytokines. Reported to act as a potent inhibitor of ADP ribosylation. Also inhibits protein synthesis and alters the phosphorylation state of several cytosolic proteins.
      FormWhite to yellow solid
      CAS number1476-53-5
      RTECSRD5425000
      Chemical formulaC₃₁H₃₅N₂O₁₁ · Na
      Purity≥90% by HPLC
      SolubilityH₂O (50 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, refrigerate (4°C). Stock solutions are stable for 3 months at 4°C.
      Toxicity Harmful
      Merck USA index14, 6722
      ReferencesMarcu, M.G., et al. 2000. J. Natl. Cancer Inst. 92, 242.
      Luhrmann, A., et al. 1998. Antimicrob. Agents Chemotherp. 42, 1911.
      Hooper, D.C., et al. 1984. Antimicrob. Agents Chemother. 25, 586.
      Lockshon, D., and Morris, D.R. 1983. Nucleic Acid. Res. 11, 2999.
      Sumiyoshi, Y., et al. 1983. J. Gen. Virol. 64, 2329.
      Staudenbauer, W.L. 1975. J. Mol. Biol. 96, 201.

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      カテゴリー

      Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Cell Cycle/Cell Division > DNA and RNA Polymerase Inhibitors