Millipore Sigma Vibrant Logo

475911 Myeloperoxidase, Human Polymorphonuclear Leukocytes

A lysosomal enzyme that catalyzes oxidations by hydrogen peroxide, including MPO-chloride-mediated killing of microbes and tumor cells, inactivation of chemotactic factors, and cross-linking of proteins.

Myeloperoxidase, Human Polymorphonuclear Leukocytes: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。

同義語: MPO

View This Product on Sigma-Aldrich
475911
価格＆在庫状況を照会

概要

Replacement Information

価格＆在庫状況

カタログ番号 在庫状況包装 Qty/Pk 価格 数量
475911-100UGCN
在庫状況検索中…
—
現在国内在庫なし 現在国内在庫なし
現在国内在庫有り 
販売中止
在庫僅少
現在国内在庫あり
    Remaining : Will advise
      Remaining : Will advise
      注文対象外
      お問合せください
      Contact Customer Service

      		 樹脂ｱﾝﾌﾟﾙ 100 μg
      価格を検索中…
      価格が見つかりません
      Minimum Quantity needs to be mulitiple of
      Maximum Quantity is
      弊社照会 詳細を表示　
      値引
      ()
       
      —
      弊社照会
      		 —
      Description
      OverviewNative, human myeloperoxidase from polymorphonuclear leukocytes. A lysosomal enzyme that catalyzes oxidations by hydrogen peroxide, including MPO-chloride-mediated killing of microbes and tumor cells, inactivation of chemotactic factors, and cross-linking of proteins. MPO catalyzes the formation of hypochlorous acid that kills bacteria either by binding the halide ion to intracellular constituents or by oxidation of bacterial lipids and proteins.
      Catalogue Number475911
      Brand Family Calbiochem®
      SynonymsMPO
      References
      ReferencesNauseef, W.M., et al. 1998. J. Leukocyte Biol. 63, 264.
      Panasenko, O.M., et al. 1994. Free Radic. Biol. Med. 16, 143.
      Mulligan, M.S., et al. 1992. Br. J. Pharmacol. 107, 1159.
      Sharonov, B.P., and Churilova, I.V. 1992. Biochem. Biophys. Res. Commun. 189, 1129.
      Product Information
      CAS number9003-99-0
      Unit of DefinitionOne unit is defined as the amount of enzyme that will reduce 1.0 µmol H₂O₂ per min at 25°C, pH 6.0.
      EC number1.11.1.7
      FormLyophilized
      FormulationLyophilized from 100-700 mM NaCl, 50 mM sodium acetate buffer, pH 6.0.
      Quality LevelMQ200
      Applications
      Biological Information
      Purity≥95% by SDS-PAGE
      SourcePrepared from blood that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Specific Activity150-200 units/mg protein
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C or -70°C). Stock solutions are stable for up to 1 year at -20°C or -70°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      カタログ番号 GTIN
      475911-100UGCN 04055977203103

      Documentation

      Myeloperoxidase, Human Polymorphonuclear Leukocytes (M)SDS

      タイトル

      英語版製品安全データシート（(M)SDS） 

      Myeloperoxidase, Human Polymorphonuclear Leukocytes 試験成績書（CoA）

      タイトルロット番号
      475911

      参考資料

      参考資料の概要
      Nauseef, W.M., et al. 1998. J. Leukocyte Biol. 63, 264.
      Panasenko, O.M., et al. 1994. Free Radic. Biol. Med. 16, 143.
      Mulligan, M.S., et al. 1992. Br. J. Pharmacol. 107, 1159.
      Sharonov, B.P., and Churilova, I.V. 1992. Biochem. Biophys. Res. Commun. 189, 1129.

      引用

      Title
    • Armin Schnabel, Elena Csernok, Jorg Braun, Wolfgang Gross. (2000) Activation of Neutrophils, Eosinophils, and Lymphocytes in the Lower Respiratory Tract in Wegener's Granulomatosis. American Journal of Critical Care Medicine 161, 399-405.
      		•
      データシート

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision11-August-2008 RFH
      SynonymsMPO
      DescriptionNative, human myeloperoxidase from polymorphonuclear leukocytes. A lysosomal enzyme that catalyzes oxidations by hydrogen peroxide, including MPO-chloride-mediated killing of microbes and tumor cells, inactivation of chemotactic factors, and cross-linking of proteins. MPO catalyzes the formation of hypochlorous acid that kills bacteria either by binding the halide ion to intracellular constituents or by oxidation of bacterial lipids and proteins.
      FormLyophilized
      FormulationLyophilized from 100-700 mM NaCl, 50 mM sodium acetate buffer, pH 6.0.
      SourcePrepared from blood that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      CAS number9003-99-0
      EC number1.11.1.7
      Purity≥95% by SDS-PAGE
      Specific activity150-200 units/mg protein
      Unit definitionOne unit is defined as the amount of enzyme that will reduce 1.0 µmol H₂O₂ per min at 25°C, pH 6.0.
      SolubilityH₂O (volume is lot-specific and can be found on the product label). Further dilute in 100 mM NaCl, 50 mM sodium acetate, pH 6.0. Enzyme may precipitate out of solution in low ionic strength buffers or in distilled H₂O.
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C or -70°C). Stock solutions are stable for up to 1 year at -20°C or -70°C.
      Toxicity Standard Handling
      ReferencesNauseef, W.M., et al. 1998. J. Leukocyte Biol. 63, 264.
      Panasenko, O.M., et al. 1994. Free Radic. Biol. Med. 16, 143.
      Mulligan, M.S., et al. 1992. Br. J. Pharmacol. 107, 1159.
      Sharonov, B.P., and Churilova, I.V. 1992. Biochem. Biophys. Res. Commun. 189, 1129.
      Citation
    • Armin Schnabel, Elena Csernok, Jorg Braun, Wolfgang Gross. (2000) Activation of Neutrophils, Eosinophils, and Lymphocytes in the Lower Respiratory Tract in Wegener's Granulomatosis. American Journal of Critical Care Medicine 161, 399-405.
      		•