Custom Premix Selecting "Custom Premix" option means that all of the beads you have chosen will be premixed in manufacturing before the kit is sent to you.
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Ordering Description
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List
この品目はお気に入りに追加されました。
動物種
パネルタイプ
選択したキット
数量
カタログ番号
注文内容
Qty/Pk
価格
96-Well Plate
数量
カタログ番号
注文内容
Qty/Pk
価格
その他の試薬を追加 （MAPmatesとともに使用するにはバッファーおよび検出キットが必要です）
数量
カタログ番号
注文内容
Qty/Pk
価格
48-602MAG
Buffer Detection Kit for Magnetic Beads
1 Kit
Space Saver Option（チェックを入れると箱詰めから袋詰めに変更となりますのでご注意ください） Customers purchasing multiple kits may choose to save storage space by eliminating the kit packaging and receiving their multiplex assay components in plastic bags for more compact storage.
Inhibits thymidylate synthetase, is a nonselective de novo purine synthesis inhibitor, and has a significant toxicity profile including hepatotoxicity, pneumonitis, and bone marrow suppression. Potent folic acid antagonist. Induces apoptosis in HL-60 human leukemia cells. Also useful as an antitumor agent.
Catalogue Number
454126
Brand Family
Calbiochem®
References
References
Kaufman, S.H., et al. 1993. Cancer Res.53, 3976. Takasuga, A., et al. 1992. J. Biochem.112, 652. Hirata, S., et al. 1989. Arthritis Rheum. 32, 1065. Jolivet, J., et al. 1983. New Engl. J. Med. 309, 1094.
Toxic by inhalation, in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin. May cause cancer. May cause heritable genetic damage.
S Phrase
S: 22-24/25-36/37/39
Do not breathe dust. Avoid contact with skin and eyes. Wear suitable protective clothing, gloves and eye/face protection.
Product Usage Statements
Storage and Shipping Information
Ship Code
Ambient Temperature Only
Toxicity
Toxic
Hazardous Materials Attention:
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage
+2°C to +8°C
Protect from Light
Protect from light
Do not freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Methotrexate - CAS 59-05-2 - Calbiochem 試験成績書（CoA）
タイトル
ロット番号
454126
参考資料
参考資料の概要
Kaufman, S.H., et al. 1993. Cancer Res.53, 3976. Takasuga, A., et al. 1992. J. Biochem.112, 652. Hirata, S., et al. 1989. Arthritis Rheum. 32, 1065. Jolivet, J., et al. 1983. New Engl. J. Med. 309, 1094.
データシート
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
13-October-2010 RFH
Description
Inhibits thymidylate synthetase, is a nonselective de novo purine synthesis inhibitor and has a significant toxicity profile including hepatotoxicity, pneumonitis and bone marrow suppression. Potent folic acid antagonist. Induces apoptosis in HL-60 human leukemia cells. Also useful as an anti-tumor agent.
Form
Yellow solid
CAS number
59-05-2
Chemical formula
C₂₀H₂₂N₈O₅ • 3H₂O
Structure formula
Purity
≥98% by HPLC
Solubility
DMSO (100 mg/ml)
Storage
Protect from light
+2°C to +8°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity
Toxic
Merck USA index
14, 5985
References
Kaufman, S.H., et al. 1993. Cancer Res.53, 3976. Takasuga, A., et al. 1992. J. Biochem.112, 652. Hirata, S., et al. 1989. Arthritis Rheum. 32, 1065. Jolivet, J., et al. 1983. New Engl. J. Med. 309, 1094.
