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Merck

MAGPMAG-24K

MILLIPLEX® Mouse Angiogenesis/Growth Factor Panel 1

Configurable Mouse Angiogenesis/Growth Factor 27-Plex Panel 1

別名:

Luminex mouse angiogenesis assay, Millipore mouse angiogenesis panel, mouse growth factor multiplex kit, mouse multiplex cancer panel, mouse oncology kit

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この商品について

UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000


製品名

MILLIPLEX® Mouse Angiogenesis/Growth Factor Panel 1,

Quality Segment

description

Configurable Mouse Angiogenesis/Growth Factor 27-Plex Panel 1

species reactivity

mouse

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

assay range

accuracy: 90-104%, standard curve range: 1-1,000 pg/mL
(Endothelin-1), standard curve range: 137-100,000 pg/mL
(Follistatin), standard curve range: 137-100,000 pg/mL
(HGF), standard curve range: 137-100,000 pg/mL
(SDF-1), standard curve range: 14-10,000 pg/mL
(IL-1b), standard curve range: 14-10,000 pg/mL
(Leptin), standard curve range: 14-10,000 pg/mL
(MIP-1α), standard curve range: 14-10,000 pg/mL
(sALK-1), standard curve range: 14-10,000 pg/mL
(sCD31/ PECAM-1), standard curve range: 27-20,000 pg/mL
(Angiopoietin-2), standard curve range: 27-20,000 pg/mL
(EGF), standard curve range: 27-20,000 pg/mL
(Endoglin), standard curve range: 27-20,000 pg/mL
(MCP-1), standard curve range: 27-20,000 pg/mL
(VEGF-C), standard curve range: 3-2,000 pg/mL
(PLGF-2), standard curve range: 6-4,000 pg/mL
(TNFα), standard curve range: 6-4,000 pg/mL
(VEGF-A), standard curve range: 69-50,000 pg/mL
(FGF-2/FGF-basic), standard curve range: 69-50,000 pg/mL
(Prolactin), standard curve range: 69-50,000 pg/mL
(VEGF-D), standard curve range: 69-50,000 pg/mL
(sFasL), standard curve range: 7-5,000 pg/mL
(Amphiregulin), standard curve range: 7-5,000 pg/mL
(Betacellulin), standard curve range: 7-5,000 pg/mL
(G-CSF), standard curve range: 7-5,000 pg/mL
(IL-17A), standard curve range: 7-5,000 pg/mL
(IL-6), standard curve range: 7-5,000 pg/mL
(KC/CXCL1)

technique(s)

multiplexing: suitable

input

cell culture supernatant(s)
plasma
tissue/cellular extract(s)
serum

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

General description

Angiogenesis, the development of new vascular networks, is a key process in normal growth and development as well as in wound healing, with homeostasis maintained by a delicate balance of angiogenic factors and inhibitors. Consequently, insufficient, or excessive blood vessel growth underlies many diseases, including cardiovascular disease, diabetic ulcers, macular degeneration, and cancer. Angiogenesis plays a significant role in tumor growth and metastasis.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 27 analytes in mouse serum, plasma, cell culture supernatants, and cell/tissue extracts.

Analytes included: sALK-1, Amphiregulin, Angiopoietin-2, Betacellulin, sCD31/sPECAM-1, EGF, Endoglin, Endothelin-1, sFasL, FGF-2 (FGF-basic), Follistatin (FST), G-CSF, HGF, IL-1β, IL-6, IL-17A (CTLA8), KC (GRO/CINC-1/CXCL1), Leptin, MCP-1 (CCL2), MIP-1α (CCL3), Placental Growth Factor 2 (PLGF-2), Prolactin, SDF-1 (CXCL12), TNF-α, VEGF-A, VEGF-C, VEGF-D

Note: Sample type must be selected when configuring this kit. Angiopeoitin-2, Betacellulin, and PECAM-1 should not be run in serum/plasma samples.

Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

Multiplex Capability: Simultaneous quantification of up to 24 analytes in serum/plasma or 27 analytes in cell culture samples, including key angiogenesis and growth factors such as VEGF-A, TNFα, IL-6, FGF-2, and more.

Wide Dynamic Range: Standard curve ranges vary by analyte, covering low to high pg/mL concentrations.

Flexible Sample Types: Compatible with mouse serum, plasma, tissue/cell culture supernatants or lysates.

Supports Studies on Tumor Microenvironment: Helps investigate how hypoxia, inflammation, and cytokine signaling contribute to abnormal vascularization in tumors.

Supports Translational Research: Enables biomarker discovery in mouse models that mimic human disease, supporting translational studies in oncology, inflammation, and vascular biology.

Legal Information

Luminex is a registered trademark of Luminex Corporation
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.


signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

保管分類

10 - Combustible liquids

wgk

WGK 3


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Please refer to KIT Component information

pdsc

Please refer to KIT Component information

prtr

Please refer to KIT Component information

fsl

Please refer to KIT Component information

ishl_indicated

Please refer to KIT Component information

ishl_notified

Please refer to KIT Component information

cart

キットコンポーネントの情報を参照してください

jan



試験成績書(COA)

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関連コンテンツ

The angiogenesis pathway is complex with many targets to analyze. Simultaneous quantification of multiple markers, with the MILLIPLEX® Human Angiogenesis/Growth Factor Panel 1, saves valuable resources. See how this panel was used to correlate angiogenesis biomarkers with early metastatic progression in NSCLC.

MILLIPLEX® マルチプレックスがんアッセイでがんバイオマーカーを検出することにより、腫瘍形成プロセスの研究が加速し、がん研究の進展に役立ちます。

Cancer biomarker detection through MILLIPLEX® multiplex cancer assays can accelerate studies of tumorigenic processes helping advance cancer research.

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