420320 Sigma-AldrichKT5720 - CAS 108068-98-0 - Calbiochem
KT5720, CAS 108068-98-0, is a cell-permeable, potent, specific, reversible, ATP-competitive inhibitor of protein kinase A (Ki = 56 nM). Has no significant effect on PKC, PKG & MLCK.
More>> KT5720, CAS 108068-98-0, is a cell-permeable, potent, specific, reversible, ATP-competitive inhibitor of protein kinase A (Ki = 56 nM). Has no significant effect on PKC, PKG & MLCK. Less<<同義語: PKA Inhibitor VII
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概要
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主要スペック表
CAS # | Empirical Formula |
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108068-98-0 | C₃₂H₃₁N₃O₅ |
価格&在庫状況
カタログ番号 | 在庫状況 | 包装 | Qty/Pk | 価格 | 数量 | |
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420320-100UGCN |
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ガラスビン | 100 μg |
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420320-50UGCN |
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樹脂アンプル | 50 μg |
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Description | |
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Overview | A potent, specific, cell-permeable, reversible and ATP-competitive inhibitor of protein kinase A (Ki = 56 nM) that is prepared by a chemical modification of K-252a. Does not significantly affect the activities of PKC, PKG, and MLCK. Inhibits axon branching in cultured neurons. A 2 mM (50 µg/47 µl) solution of KT 5720 (Cat. No. 420323) in DMSO is also available. |
Catalogue Number | 420320 |
Brand Family | Calbiochem® |
Synonyms | PKA Inhibitor VII |
Product Information | |
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CAS number | 108068-98-0 |
ATP Competitive | Y |
Form | White solid |
Hill Formula | C₃₂H₃₁N₃O₅ |
Chemical formula | C₃₂H₃₁N₃O₅ |
Reversible | Y |
Structure formula Image | |
Quality Level | MQ100 |
Biological Information | |
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Primary Target | PKA |
Primary Target K<sub>i</sub> | 56 nM for protein kinase A |
Purity | ≥95% by HPLC |
Physicochemical Information | |
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Cell permeable | Y |
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Materials Information |
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Safety Information according to GHS |
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Supplemental Information |
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Specifications |
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Global Trade Item Number | |
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カタログ番号 | GTIN |
420320-100UGCN | 04055977211023 |
420320-50UGCN | 04055977211030 |
Documentation
KT5720 - CAS 108068-98-0 - Calbiochem (M)SDS
タイトル |
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KT5720 - CAS 108068-98-0 - Calbiochem 試験成績書(CoA)
タイトル | ロット番号 |
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420320 |
参考資料
参考資料の概要 |
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Simpson, C.S., and Morris, B.J. 1995. Neuroscience 68, 97. Cabell, L., and Audesirk, G. 1993. Int. J. Dev. Neurosci. 11, 357. Gadbois, D.M., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 8626. Kase, H., et al. 1987. Biochem. Biophys. Res. Commun. 142, 436. |
引用
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