Millipore Sigma Vibrant Logo

420136 JNK Inhibitor IX - CAS 312917-14-9 - Calbiochem

The JNK Inhibitor IX, also referenced under CAS 312917-14-9, controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

JNK Inhibitor IX - CAS 312917-14-9 - Calbiochem: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。

同義語: N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)-1-naphthamide

Primary Target: JNK2 and JNK3
View This Product on Sigma-Aldrich
420136
価格＆在庫状況を照会

概要

Replacement Information

主要スペック表

CAS #Empirical Formula
312917-14-9C₂₀H₁₆N₂OS • H₂O

価格＆在庫状況

カタログ番号 在庫状況包装 Qty/Pk 価格 数量
420136-5MGCN
在庫状況検索中…
—
現在国内在庫なし 現在国内在庫なし
現在国内在庫有り 
販売中止
在庫僅少
現在国内在庫あり
    Remaining : Will advise
      Remaining : Will advise
      注文対象外
      お問合せください
      Contact Customer Service

      		 樹脂ｱﾝﾌﾟﾙ 5 mg
      価格を検索中…
      価格が見つかりません
      Minimum Quantity needs to be mulitiple of
      Maximum Quantity is
      弊社照会 詳細を表示　
      値引
      ()
       
      —
      弊社照会
      		 —
      Description
      OverviewA thienylnaphthamide compound that acts as a potent and ATP binding site-targeting inhibitor of JNK2 and JNK3 (pIC50 = 6.5 and 6.7, respectively) with little or no activity against JNK1, p38α, and a panel of more than 30 other kinases (pIC50 <5.0). In contrast, SP600125 (Cat. Nos. 420119 and 420128) offers little selectivity between JNK1 and JNK3 (pIC50 = 6.4 and 5.9, respectively) under the same assay conditions.
      Catalogue Number420136
      Brand Family Calbiochem®
      SynonymsN-(3-Cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)-1-naphthamide
      References
      ReferencesAngell, R.M., et al. 2007. Bioorg. Med. Chem. Lett. 17, 1296.
      Product Information
      CAS number312917-14-9
      ATP CompetitiveY
      FormTan solid
      Hill FormulaC₂₀H₁₆N₂OS • H₂O
      Chemical formulaC₂₀H₁₆N₂OS • H₂O
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetJNK2 and JNK3
      Primary Target IC<sub>50</sub>pIC50 = 6.5 and 6.7, against JNK2 and JNK3, respectively
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 36/37/38

      Irritating to eyes, respiratory system and skin.
      S PhraseS: 26-36-45

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Irritant
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      カタログ番号 GTIN
      420136-5MGCN 04055977187663

      Documentation

      JNK Inhibitor IX - CAS 312917-14-9 - Calbiochem (M)SDS

      タイトル

      英語版製品安全データシート（(M)SDS） 

      JNK Inhibitor IX - CAS 312917-14-9 - Calbiochem 試験成績書（CoA）

      タイトルロット番号
      420136

      参考資料

      参考資料の概要
      Angell, R.M., et al. 2007. Bioorg. Med. Chem. Lett. 17, 1296.

      Posters

      タイトル
      Human Kinome & InhibitorSelect™ Libraries
      データシート

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision05-October-2007 JSW
      SynonymsN-(3-Cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)-1-naphthamide
      DescriptionA thienylnaphthamide compound that acts as a potent and ATP binding site-targeting inhibitor of JNK2 and JNK3 (pIC50 = 6.5 and 6.7, respectively) with little or no activity against JNK1, p38α, and a panel of more than 30 other kinases (pIC50 <5.0). In contrast, SP600125 (Cat. Nos. 420119 and 420128) offers little selectivity between JNK1 and JNK3 (pIC50 = 6.4 and 5.9, respectively) under the same assay conditions.
      FormTan solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number312917-14-9
      Chemical formulaC₂₀H₁₆N₂OS • H₂O
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityDMSO (10 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Irritant
      ReferencesAngell, R.M., et al. 2007. Bioorg. Med. Chem. Lett. 17, 1296.