Millipore Sigma Vibrant Logo

420123 JNK Inhibitor II, Negative Control - CAS 54642-23-8 - Calbiochem

View This Product on Sigma-Aldrich
420123
価格&在庫状況を照会

概要

Replacement Information

主要スペック表

CAS #Empirical Formula
54642-23-8C₁₅H₁₀N₂O

価格&在庫状況

カタログ番号 在庫状況包装 Qty/Pk 価格 数量
420123-1MGCN
在庫状況検索中…
現在国内在庫なし
現在国内在庫なし
現在国内在庫有り 
販売中止
在庫僅少
現在国内在庫あり
    Remaining : Will advise
      Remaining : Will advise
      注文対象外
      お問合せください
      Contact Customer Service

      樹脂アンプル 1 mg
      価格を検索中…
      価格が見つかりません
      Minimum Quantity needs to be mulitiple of
      Maximum Quantity is
      弊社照会 詳細を表示 
      値引
      ()
       
      弊社照会
      Description
      OverviewA useful negative control for JNK Inhibitor II (SP600125, Cat. No. 420119). Inhibits JNK2 and JNK3 only at much higher concentrations (IC50 = 18 µM and 24 µM, respectively) compared to SP600125 (IC50 = 40 nM and 90 nM, respectively).
      Catalogue Number420123
      Brand Family Calbiochem®
      SynonymsN¹-Methyl-1,9-pyrazoloanthrone
      References
      ReferencesShin, M., and Boyd, Y.D. 2002. Biochim. Biophys. Acta 1589, 311.
      Bennett, B.L., et al. 2001. Proc. Natl. Acad. Sci. USA 98, 13681.
      Product Information
      CAS number54642-23-8
      ATP CompetitiveY
      FormYellow solid
      Hill FormulaC₁₅H₁₀N₂O
      Chemical formulaC₁₅H₁₀N₂O
      ReversibleY
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetA useful negative control for JNK Inhibitor II (SP600125, Cat. No. 420119)
      Primary Target IC<sub>50</sub>18 µM and 24 µM against JNK2 and JNK3, respectively
      Purity≥97% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      カタログ番号 GTIN
      420123-1MGCN 04055977188035

      Documentation

      JNK Inhibitor II, Negative Control - CAS 54642-23-8 - Calbiochem (M)SDS

      タイトル

      英語版製品安全データシート((M)SDS) 

      JNK Inhibitor II, Negative Control - CAS 54642-23-8 - Calbiochem 試験成績書(CoA)

      タイトルロット番号
      420123

      参考資料

      参考資料の概要
      Shin, M., and Boyd, Y.D. 2002. Biochim. Biophys. Acta 1589, 311.
      Bennett, B.L., et al. 2001. Proc. Natl. Acad. Sci. USA 98, 13681.

      引用

      Title
    • Alexandra Thiel, Mira Heinonen, Johanna Rintahaka, Tuija Hallikainen, and Annabrita Hemmes, Dan A. Dixon, Caj Haglund, and Ari Ristimaki. (2006) EXPRESSION OF CYCLOOXYGENASE-2 IS REGULATED BY GSK-3 IN GASTRIC CANCER CELLS. Journal of Biological Chemistry in press,.
    • データシート

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision13-April-2011 RFH
      SynonymsN¹-Methyl-1,9-pyrazoloanthrone
      DescriptionA useful negative control for JNK Inhibitor II (SP600125, Cat. No. 420119). Inhibits JNK2 and JNK3 only at much higher concentrations (IC50 = 18 µM and 24 µM, respectively) compared to SP600125 (IC50 = 40 nM and 90 nM, respectively).
      FormYellow solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number54642-23-8
      Chemical formulaC₁₅H₁₀N₂O
      Structure formulaStructure formula
      Purity≥97% by HPLC
      SolubilityDMSO (10 mg/ml)
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesShin, M., and Boyd, Y.D. 2002. Biochim. Biophys. Acta 1589, 311.
      Bennett, B.L., et al. 2001. Proc. Natl. Acad. Sci. USA 98, 13681.
      Citation
    • Alexandra Thiel, Mira Heinonen, Johanna Rintahaka, Tuija Hallikainen, and Annabrita Hemmes, Dan A. Dixon, Caj Haglund, and Ari Ristimaki. (2006) EXPRESSION OF CYCLOOXYGENASE-2 IS REGULATED BY GSK-3 IN GASTRIC CANCER CELLS. Journal of Biological Chemistry in press,.