Millipore Sigma Vibrant Logo

508507 Isradipine - CAS 75695-93-1 - Calbiochem

A voltage gated calcium channel gating inhibitor of the dihydropyridine class.

Isradipine - CAS 75695-93-1 - Calbiochem: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。

同義語: L-type voltage-gated Ca2+ channel blocker, Isradipine, PN 200-110

Primary Target: CaV
View This Product on Sigma-Aldrich
508507
価格＆在庫状況を照会

概要

Replacement Information

主要スペック表

CAS #Empirical Formula
75695-93-1C₁₉H₂₁N₃O₅

価格＆在庫状況

カタログ番号 在庫状況包装 Qty/Pk 価格 数量
5.08507.0001
在庫状況検索中…
—
現在国内在庫なし 現在国内在庫なし
現在国内在庫有り 
販売中止
在庫僅少
現在国内在庫あり
    Remaining : Will advise
      Remaining : Will advise
      注文対象外
      お問合せください
      Contact Customer Service

      		 ｶﾞﾗｽﾋﾞﾝ 10 mg
      価格を検索中…
      価格が見つかりません
      Minimum Quantity needs to be mulitiple of
      Maximum Quantity is
      弊社照会 詳細を表示　
      値引
      ()
       
      —
      弊社照会
      		 —
      Description
      OverviewA water soluble voltage gated calcium channel gating inhibitor of the dihydropyridine class. In human ion channels, Isradipine has gating inhibition on Cav1.4 channels (1x10E-6 M) and Cav1.3 (3x10E-8) and in mouse ion channels a pIC50 of 6.7. Often prescribed for hypertension (trade names DynaCirc, Prescal), recent animal models suggest a use in Parkinson′s Disease.

      Please note that the molecular weight for this compound is batch-specific due to variable water content.
      Catalogue Number508507
      Brand Family Calbiochem®
      SynonymsL-type voltage-gated Ca2+ channel blocker, Isradipine, PN 200-110
      References
      ReferencesChan, C. S. et al. 2007. Nature. 447, 1081.
      Baumann, L. et al. 2004. Invest. Ophthalmol. Vis. Sci. 45, 708.
      Koschak, A. et al. 2003. J. Neurosci./i> 23, 6041.
      Koschak, A. et al. 2001. J. Biol Chem 276, 22100.
      Product Information
      CAS number75695-93-1
      FormYellow solid
      Hill FormulaC₁₉H₂₁N₃O₅
      Chemical formulaC₁₉H₂₁N₃O₅
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetCaV
      Purity≥98% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      カタログ番号 GTIN
      5.08507.0001 04055977262001

      Documentation

      Isradipine - CAS 75695-93-1 - Calbiochem (M)SDS

      タイトル

      英語版製品安全データシート（(M)SDS） 

      参考資料

      参考資料の概要
      Chan, C. S. et al. 2007. Nature. 447, 1081.
      Baumann, L. et al. 2004. Invest. Ophthalmol. Vis. Sci. 45, 708.
      Koschak, A. et al. 2003. J. Neurosci./i> 23, 6041.
      Koschak, A. et al. 2001. J. Biol Chem 276, 22100.
      データシート

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision31-January-2014 JSW
      SynonymsL-type voltage-gated Ca2+ channel blocker, Isradipine, PN 200-110
      DescriptionA water soluble voltage gated calcium channel gating inhibitor of the dihydropyridine class. In human ion channels, Isradipine has gating inhibition on Cav1.4 channels (1x10E-6 M) and Cav1.3 (3x10E-8) and in mouse ion channels a pIC50 of 6.7. Often prescribed for hypertension (trade names DynaCirc, Prescal), recent animal models suggest a use in Parkinson′s Disease.
      FormYellow solid
      CAS number75695-93-1
      Chemical formulaC₁₉H₂₁N₃O₅
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityDMSO (100 mM) or Ethanol (50 mM)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesChan, C. S. et al. 2007. Nature. 447, 1081.
      Baumann, L. et al. 2004. Invest. Ophthalmol. Vis. Sci. 45, 708.
      Koschak, A. et al. 2003. J. Neurosci./i> 23, 6041.
      Koschak, A. et al. 2001. J. Biol Chem 276, 22100.