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584223 InSolution™ Tetrahydrouridine - CAS 18771-50-1 - Calbiochem

Tetrahydrouridine is a potent competitive inhibitor of cytidine deaminase.

InSolution™ Tetrahydrouridine - CAS 18771-50-1 - Calbiochem: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。

同義語: 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-hydroxytetrahydropyrimidin-2(1H)-one, dihydrate, THU, H4U

Primary Target: cytidine deaminase
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584223
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概要

Replacement Information

主要スペック表

CAS #Empirical Formula
18771-50-1C₉H₁₆N₂O₆ • 2H₂O

価格＆在庫状況

カタログ番号 在庫状況包装 Qty/Pk 価格 数量
584223-25MGCN
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      		 ｶﾞﾗｽﾋﾞﾝ 25 mg
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      Description
      OverviewA potent competitive inhibitor of cytidine deaminase. Used in combination with cytosine arabinoside (Ara-C) to assess the anti-leukemic activity and anti-tumor activity of Ara-C in in vitro studies. The solid form of this compound (Cat. No. 584222) is also available.
      Catalogue Number584223
      Brand Family Calbiochem®
      Synonyms1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-hydroxytetrahydropyrimidin-2(1H)-one, dihydrate, THU, H4U
      References
      ReferencesYusa, K., et al. 1995. Biochem. Biophys. Res. Commun. 206, 486.
      Bouffard, D.Y., et al. 1993. Biochem Pharmacol. 45, 1857.
      Laliberte, J., et al. 1992. Cancer Chemotherap. Pharmacol. 30, 7.
      Riva, C., et al. 1992. Chemotherapy 38, 358.
      Yusa, K., et al. 1992. J. Biol. Chem. 267, 16848.
      Hanze, A.R. 1967. J. Am. Chem. Soc. 89, 6720.
      Product Information
      CAS number18771-50-1
      FormLiquid
      FormulationA 100 mM (25 mg/879 µL) solution of Tetrahydrouridine (Cat. No. 584222) in H₂O.
      Hill FormulaC₉H₁₆N₂O₆ • 2H₂O
      ReversibleY
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetcytidine deaminase
      Purity≥90% by TLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Protect from Light Protect from light
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C). Aliquots are stable for up to 6 months at -70°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      カタログ番号 GTIN
      584223-25MGCN 04055977264999

      Documentation

      InSolution™ Tetrahydrouridine - CAS 18771-50-1 - Calbiochem (M)SDS

      タイトル

      英語版製品安全データシート（(M)SDS） 

      InSolution™ Tetrahydrouridine - CAS 18771-50-1 - Calbiochem 試験成績書（CoA）

      タイトルロット番号
      584223

      参考資料

      参考資料の概要
      Yusa, K., et al. 1995. Biochem. Biophys. Res. Commun. 206, 486.
      Bouffard, D.Y., et al. 1993. Biochem Pharmacol. 45, 1857.
      Laliberte, J., et al. 1992. Cancer Chemotherap. Pharmacol. 30, 7.
      Riva, C., et al. 1992. Chemotherapy 38, 358.
      Yusa, K., et al. 1992. J. Biol. Chem. 267, 16848.
      Hanze, A.R. 1967. J. Am. Chem. Soc. 89, 6720.
      データシート

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision03-January-2019 JSW
      Synonyms1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-hydroxytetrahydropyrimidin-2(1H)-one, dihydrate, THU, H4U
      DescriptionA potent competitive inhibitor of cytidine deaminase. Used in combination with cytosine arabinoside (Ara-C) to assess the anti-leukemic activity and anti-tumor activity of Ara-C in in vitro studies. The solid form of this compound (Cat. No. 584222) is also available.
      FormLiquid
      FormulationA 100 mM (25 mg/879 µL) solution of Tetrahydrouridine (Cat. No. 584222) in H₂O.
      Intert gas (Yes/No) Packaged under inert gas
      CAS number18771-50-1
      Structure formulaStructure formula
      Purity≥90% by TLC
      Storage Protect from light
      Avoid freeze/thaw
      ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C). Aliquots are stable for up to 6 months at -70°C.
      Toxicity Standard Handling
      ReferencesYusa, K., et al. 1995. Biochem. Biophys. Res. Commun. 206, 486.
      Bouffard, D.Y., et al. 1993. Biochem Pharmacol. 45, 1857.
      Laliberte, J., et al. 1992. Cancer Chemotherap. Pharmacol. 30, 7.
      Riva, C., et al. 1992. Chemotherapy 38, 358.
      Yusa, K., et al. 1992. J. Biol. Chem. 267, 16848.
      Hanze, A.R. 1967. J. Am. Chem. Soc. 89, 6720.