573129 Sigma-AldrichInSolution™ STAT3 Inhibitor III, WP1066 - Calbiochem
The InSolution™ STAT3 Inhibitor III, WP1066, also referenced under CAS 857064-38-1, controls the biological activity of STAT3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
More>> The InSolution™ STAT3 Inhibitor III, WP1066, also referenced under CAS 857064-38-1, controls the biological activity of STAT3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Less<<InSolution™ STAT3 Inhibitor III, WP1066 - Calbiochem: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。
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概要
| Replacement Information |
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主要スペック表
| Empirical Formula |
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| C₁₇H₁₄BrN₃O |
価格＆在庫状況
| カタログ番号 | 在庫状況 | 包装 | Qty/Pk | 価格 | 数量 | |
|---|---|---|---|---|---|---|
| 573129-5MGCN |
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ｶﾞﾗｽﾋﾞﾝ | 5 mg |
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| Description | |
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| Overview | A cell-permeable AG 490 (Cat. No. 658401) tyrphostin analog that acts as an effective STAT3 pathway inhibitor and a much more potent antitumor agent than AG 490 in inhibiting malignant glioma growth both in cultures in vitro (IC50 = 5.6 and 3.7 µM in a viability assay using U87-MG and U373-MG, respectively; no inhibition against nontumor NHA at 10 µM) and in mice in vivo. Shown to cross blood-brain barrier in mice in vivo. |
| Catalogue Number | 573129 |
| Brand Family | Calbiochem® |
| References | |
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| References | Iwamaru, A., et al. 2007. Oncogene, 26, 2435. |
| Product Information | |
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| Form | Liquid |
| Formulation | A 50 mM (5 mg/281 µl) solution of STAT3 Inhibitor III, WP1066 (Cat. No. 573097) in DMSO. |
| Hill Formula | C₁₇H₁₄BrN₃O |
| Chemical formula | C₁₇H₁₄BrN₃O |
| Hygroscopic | Hygroscopic |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
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| Biological Information | |
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| Purity | ≥97% by HPLC |
| Physicochemical Information |
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| Dimensions |
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| Materials Information |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Safety Information | |
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| R Phrase | R: 36/38 Irritating to eyes and skin. |
| Product Usage Statements |
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| Packaging Information | |
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| Packaged under inert gas | Packaged under inert gas |
| Transport Information |
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| Supplemental Information |
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| Specifications |
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| Global Trade Item Number | |
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| カタログ番号 | GTIN |
| 573129-5MGCN | 04055977190199 |
Documentation
InSolution™ STAT3 Inhibitor III, WP1066 - Calbiochem (M)SDS
| タイトル |
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InSolution™ STAT3 Inhibitor III, WP1066 - Calbiochem 試験成績書（CoA）
| タイトル | ロット番号 |
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| 573129 |
参考資料
| 参考資料の概要 |
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| Iwamaru, A., et al. 2007. Oncogene, 26, 2435. |
技術情報
| タイトル |
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| JAK/STAT Signaling Research Focus |
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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