数量	カタログ番号	注文内容	Qty/Pk	価格
			96-Well Plate

数量	カタログ番号	注文内容	Qty/Pk	価格
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

444151 Sigma-AldrichInSolution™ Nutlin-3, Racemic - Calbiochem

InSolution™ Nutlin-3, Racemic - Calbiochem: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。

(M)SDS
試験成績書（CoA）
参考資料
Data Sheet

同義語: MDM2 Inhibitor IV

お勧めの製品

概要

Replacement Information

主要スペック表

Empirical Formula
C₃₀H₃₀Cl₂N₄O₄

価格＆在庫状況

カタログ番号	在庫状況	包装	Qty/Pk	価格	数量
444151-1MGCN	在庫状況検索中… — 現在国内在庫なし現在国内在庫有り販売中止在庫僅少現在国内在庫あり在庫を照会するにはログインしてください現在国内在庫有り現在国内在庫なし現在国内在庫有り Remaining : Will advise Remaining : Will advise 注文対象外お問合せください Contact Customer Service お問合せくださいお問合せください	樹脂ｱﾝﾌﾟﾙ	1 mg	価格を検索中… 価格が見つかりません Minimum Quantity needs to be mulitiple of Maximum Quantity is 弊社照会詳細を表示　値引 () — 弊社照会納入価格を閲覧するにはログインしてください	在庫状況を照会 —	お気に入り/ショッピングリストに追加お気に入り/ショッピングリストに追加お気に入りに追加されました

Description
Catalogue Number	444151
Brand Family	Calbiochem®
Synonyms	MDM2 Inhibitor IV

References
References	Thompson, T., et al. 2004. J. Biol. Chem. 279, 53015. Vassilev, L.T., et al. 2004. Science 303, 844.

Product Information
Form	Liquid
Formulation	A 10 mM (1 mg/172 µl) solution of MDM2 Antagonist, Nutlin-3, Racemic (Cat. No. 444143) in DMSO
Hill Formula	C₃₀H₃₀Cl₂N₄O₄
Chemical formula	C₃₀H₃₀Cl₂N₄O₄
Hygroscopic	Hygroscopic
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Purity	≥98% by HPLC

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information
R Phrase	R: 36/38 Irritating to eyes and skin.
S Phrase	S: 26-36-45 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

Product Usage Statements

Storage and Shipping Information
Ship Code	Shipped with Blue Ice or with Dry Ice
Toxicity	Irritant
Storage	-20°C
Protect from Light	Protect from light
Hygroscopic	Hygroscopic
Do not freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-20°C).

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
カタログ番号	GTIN
444151-1MGCN	04055977205466

Documentation

InSolution™ Nutlin-3, Racemic - Calbiochem (M)SDS

タイトル
英語版製品安全データシート（(M)SDS）

InSolution™ Nutlin-3, Racemic - Calbiochem 試験成績書（CoA）

タイトル	ロット番号
444151	ロット番号を入力

参考資料

参考資料の概要
Thompson, T., et al. 2004. J. Biol. Chem. 279, 53015. Vassilev, L.T., et al. 2004. Science 303, 844.

データシート

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	28-August-2008 JSW
Synonyms	MDM2 Inhibitor IV
Description	A cell-permeable, potent, and selective MDM2 antagonist (IC₅₀ = 90 nM for Nutlin-3a and 13.6 µM for Nutlin-3b) that displays antitumor properties. Activates the p53 pathway by binding MDM2 in the p53-binding pocket and inhibiting the MDM2-p53 interaction. Shown to induce apoptosis in several cancer cell lines with wild-type p53 and in xenografted tumor mice.
Form	Liquid
Formulation	A 10 mM (1 mg/172 µl) solution of MDM2 Antagonist, Nutlin-3, Racemic (Cat. No. 444143) in DMSO
Intert gas (Yes/No)	Packaged under inert gas
Chemical formula	C₃₀H₃₀Cl₂N₄O₄
Structure formula
Purity	≥98% by HPLC
Storage	Protect from light -20°C Hygroscopic
Do Not Freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-20°C).
Toxicity	Irritant
References	Thompson, T., et al. 2004. J. Biol. Chem. 279, 53015. Vassilev, L.T., et al. 2004. Science 303, 844.

カテゴリー

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > DNA Damage/Repair > MDM2 Inhibitors

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