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376817 Hexokinase II Inhibitor II, 3-BP - CAS 1113-59-3 - Calbiochem

The Hexokinase II Inhibitor II, 3-BP, also referenced under CAS 1113-59-3, controls the biological activity of Hexokinase II. This small molecule/inhibitor is primarily used for Cell Structure applications.

Hexokinase II Inhibitor II, 3-BP - CAS 1113-59-3 - Calbiochem: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。

同義語: 3-BrPA, Bromopyruvate, Bromopyruvatic Acid, 3-Bromo-2-oxopropionic acid

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376817
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概要

Replacement Information

主要スペック表

CAS #Empirical Formula
1113-59-3C₃H₃BrO₃

価格＆在庫状況

カタログ番号 在庫状況包装 Qty/Pk 価格 数量
376817-100MGCN
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      		 100 mg
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      Description
      OverviewA cell-permeable pyruvic acid derivative that acts as an inhibitor against hexokinase II-mediated glycolysis and effectively suppress tumor survival both in cultures in vitro and in mice and rats in vivo.
      Catalogue Number376817
      Brand Family Calbiochem®
      Synonyms3-BrPA, Bromopyruvate, Bromopyruvatic Acid, 3-Bromo-2-oxopropionic acid
      References
      ReferencesBujis, M., et al. 2009. Invest. New Drugs 27, 120.
      Chen, Z., et al. 2009. Biochim. Biophys. Acta. 1787, 553.
      Hulleman, E., et al. 2009. Blood. 113, 2014;
      Mathupala, S.P., et al. 2009. Semin. Cancer Biol. 19, 17.
      Pereira da Silva, A.P., et al. 2009. Biochem. J. 417, 717.
      Yun, J., et al. 2009. Science. 325, 1555.
      Zhang, X., et al. 2009. Anticancer Res. 29, 1443.
      Kim, J.S., et al. 2008. J. Bioenerg. Biomembr. 40, 607.
      Product Information
      CAS number1113-59-3
      EC number214-206-5
      FormWhite crystalline solid
      Hill FormulaC₃H₃BrO₃
      Chemical formulaC₃H₃BrO₃
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥97% by Titration
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSUZ0840000
      Safety Information
      R PhraseR: 34

      Causes burns.
      S PhraseS: 26-36/37/39-45

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing, gloves and eye/face protection.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Corrosive
      Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      カタログ番号 GTIN
      376817-100MGCN 04055977212983

      Documentation

      Hexokinase II Inhibitor II, 3-BP - CAS 1113-59-3 - Calbiochem (M)SDS

      タイトル

      英語版製品安全データシート（(M)SDS） 

      Hexokinase II Inhibitor II, 3-BP - CAS 1113-59-3 - Calbiochem 試験成績書（CoA）

      タイトルロット番号
      376817

      参考資料

      参考資料の概要
      Bujis, M., et al. 2009. Invest. New Drugs 27, 120.
      Chen, Z., et al. 2009. Biochim. Biophys. Acta. 1787, 553.
      Hulleman, E., et al. 2009. Blood. 113, 2014;
      Mathupala, S.P., et al. 2009. Semin. Cancer Biol. 19, 17.
      Pereira da Silva, A.P., et al. 2009. Biochem. J. 417, 717.
      Yun, J., et al. 2009. Science. 325, 1555.
      Zhang, X., et al. 2009. Anticancer Res. 29, 1443.
      Kim, J.S., et al. 2008. J. Bioenerg. Biomembr. 40, 607.
      データシート

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision02-December-2010 RFH
      Synonyms3-BrPA, Bromopyruvate, Bromopyruvatic Acid, 3-Bromo-2-oxopropionic acid
      DescriptionA cell-permeable pyruvic acid derivative that acts as an inhibitor against hexokinase II-mediated glycolysis and effectively suppress tumor survival both in cultures in vitro and in mice and rats in vivo.
      FormWhite crystalline solid
      CAS number1113-59-3
      RTECSUZ0840000
      EC number214-206-5
      Chemical formulaC₃H₃BrO₃
      Structure formulaStructure formula
      Purity≥97% by Titration
      SolubilityDMSO (100 mg/ml) or dH₂O (100 mg/ml)
      Storage +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Corrosive
      ReferencesBujis, M., et al. 2009. Invest. New Drugs 27, 120.
      Chen, Z., et al. 2009. Biochim. Biophys. Acta. 1787, 553.
      Hulleman, E., et al. 2009. Blood. 113, 2014;
      Mathupala, S.P., et al. 2009. Semin. Cancer Biol. 19, 17.
      Pereira da Silva, A.P., et al. 2009. Biochem. J. 417, 717.
      Yun, J., et al. 2009. Science. 325, 1555.
      Zhang, X., et al. 2009. Anticancer Res. 29, 1443.
      Kim, J.S., et al. 2008. J. Bioenerg. Biomembr. 40, 607.